 Giant Cell Tumor of Tendon Sheath
"Giant Cell Tumor of Tendon Sheath" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor arising in the SYNOVIAL MEMBRANE; SYNOVIAL BURSA; or TENDON sheath. It is characterized by OSTEOCLAST-like GIANT CELLS; FOAM CELLS; pigmented HEMOSIDERIN-laden MACROPHAGES and inflammatory infiltrate. It is classified either as diffuse or localized tenosynovitis.
| Descriptor ID |
D000070779
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| MeSH Number(s) |
C04.557.450.565.380.690 C05.550.870.445 C05.651.869.762
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| Concept/Terms |
Localized Giant Cell Tumor of the Tendon Sheath- Localized Giant Cell Tumor of the Tendon Sheath
- Localized Nodular Tenosynovitis
- Localized Nodular Tenosynovitides
- Nodular Tenosynovitides, Localized
- Nodular Tenosynovitis, Localized
- Tenosynovitides, Localized Nodular
- Tenosynovitis, Localized Nodular
- Localized Pigmented Villonodular Synovitis
- Nodular Tenosynovitis
- Nodular Tenosynovitides
- Tenosynovitides, Nodular
- Tenosynovitis, Nodular
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Below are MeSH descriptors whose meaning is more general than "Giant Cell Tumor of Tendon Sheath".
Below are MeSH descriptors whose meaning is more specific than "Giant Cell Tumor of Tendon Sheath".
This graph shows the total number of publications written about "Giant Cell Tumor of Tendon Sheath" by people in this website by year, and whether "Giant Cell Tumor of Tendon Sheath" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2021 | 3 | 0 | 3 | | 2022 | 1 | 0 | 1 | | 2024 | 2 | 1 | 3 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Giant Cell Tumor of Tendon Sheath" by people in Profiles.
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Jeys LM, Botello E, Boyle R, Ebeid W, Hilton T, Houdek MT, Hosking K, Kurisunkal VJ, Laubscher M, Morris GV, Puri A, Ruggieri P, Laitinen MK, Abdul Bari Y, Abood A, Abraham JA, Acosta Marin M, Agarwal M, Agarwal R, Aguirre M, Ajit Singh V, Akiyama T, Al Farii H, Alaqeel M, Alaseem A, Aldosari O, Alexander K, Alfaro P, Aljuhani W, Allison DC, Almashahedi M, Alotaibi A, Alpan B, Alshaygy IS, Althunayan T, Andreani L, Andreou D, Andriandi A, Annabelle L, Aponte-Tinao L, Ardelt M, Armas S, Aston W, Aycan OE, Baad-Hansen T, Baeza P, Baird C, Balach T, Banse X, Barriga J, Barry J, Basile G, Bastoni S, Basuki MH, Bauer HC, Baydar S, Bayliss L, Becker R, Bedi A, Benevenia J, Bengoa F, Berger C, Bernthal N, Binitie O, Bird J, Bobseit A, Bodian C, Boffano M, Bonilla Huertas P, Bramer J, Broadhead M, Broekhuis D, Broida SE, Brown D, Bruschi A, Budny T, Buist M, Burke Z, Busse T, Cabrolier J, Calvo-Haro JA, Campanacci DA, Cardoso R, Carey Smith R, Carrasco MG, Casales N, Castan A, Ceballos O, Chan CM, Chan L, Chang LZ, Charoenlap C, Chaustre Florez JF, Chin J, Choong P, Chrobok A, Chung YG, Ciechanowicz D, Clara-Altamirano MA, Consuegra Guzman LA, Cornu O, Coubeau L, Courtot L, Crawford B, Cribb G, Cuervo-Lozano CE, Dammerer D, de la Rosa P, de Lima Corvino D, De Paolis M, De Santos de la Fuente FJ, de Vaal M, Deisenhofer JM, Delgado Obando J, Demir E, Deo S, Deventer N, Di Bella C, Dierselhuis E, Docquier PL, Domson G, Donati DM, Doshi A, Duivenvoorden MJC, Duran-Ciarrochi R, Dürr HR, Ehlers PJ, El Ghoneimy AM, El Motassime A, Eloi Pinto FF, Endo M, Epstein G, Eralp L, Etaiwi M, Eward W, Fabbri N, Faimali M, Farman U, Farooq A, Farooque K, Farris C, Ferguson P, Ferreira N, Fiorenza F, Flint M, Forsberg JA, Franks D, Freitas JP, Fuchs B, Fujiwara T, Funovics PT, Fuzy E, Galli Serra M, Gamie Z, Garcia-Carrasco M, García-Huidobro G, Gaston CL, Gazendam A, Georges B, Ghert M, Ghosh KM, Giardina FL, Gibbs CP, Golovina Y, Gomez Mier LC, Gomez-Mascard A, Gomez-Sierra MA, González-Browne C, Gonzalez-Saldivar J, González-Motta A, Gortzak Y, Gosheger G, Gouin F, Goulding K, Gracia I, Graydon A, Green N, Griffin A, Guedes A, Gulia A, Gupta S, Guzman M, Hardes J, Hasan YO, Hashim AM, Havard H, Haydon R, Hegde P, Hernandez Lopez A, Herrera D, Hesham A, Hesla A, Hess M, Hirschmann A, Hobusch G, Hohensteiner A, Hongsaprabhas C, Hornicek F, Hsu M, Idowu OK, Idulhaq M, Igbinoba B, Ippolito JA, Iwata S, Jagiello J, Johan MP, Johnson L, Johnston A, Joo MW, Joyce D, Jung B, Jungels C, Jutte P, Jutte W, Jääskeläinen AS, Kaldas K, Kapanci B, Karaca MO, Kawai A, Kemp A, Khal AA, Khan Z, Khan ZA, Khaouam N, Kim HS, Klopper S, Kobayashi E, Kobayashi H, Kontogeorgakos V, Kotrych D, Krebbekx GGJ, Krishnamurthy AV, Kunisada T, Kyte R, Lacroix V, Lazarides A, Le Nail LR, Lee FY, Lee J, Lee M, Legosz P, Lehner B, Leithner A, Leone G, Letson D, Lewis VO, Li B, Liikanen H, Lin P, Linda Z, Lindsay S, Lozano Calderon S, Lutomia Lumbasi M, Macdonald J, Machado P, Majirija E, Malina M, Malyk R, Marais L, Mascard E, Mattei JC, McCullough L, McMahon S, Medellin Rincon MR, Mediavilla Santos L, Meijer D, Meijer JG, Miller B, Molloy A, Moriel Garcesco DJ, Morris CD, Morse-Sanyal A, Mottard S, Mthethwa PG, Muñoz-Montecinos C, Murcia M, Müller M, Nakayama R, Narhari P, Nasar A, Nayak P, Neugebauer J, Nieminen J, Ntombela P, Nystrom L, O'Reilly-Harbidge S, O'Toole G, Ogura K, Oktayana MD, Oliveira V, Olivier A, Olson D, Olusunmade O, Omar M, Omran Hasan Y, Ortiz-Cruz EJ, Ozaki S, Ozaki T, Ozkan K, Pala E, Palmerini E, Panchwagh Y, Pang G, Papagelopoulos P, Papagelopoulos DP, Paraliticci G, Parizzia W, Parry M, Pate M, Peiró A, Perera J, Petersen MM, Phakathi O, Phimolsarnti R, Phiri T, Pinheiro R, Pinto Santander N, Ploegmakers J, Pollock R, Powell G, Prabowo Y, Pruthi M, Puhaindran M, Quirion J, Quirland C, Rabin E, Rachbauer A, Radhakrishnan S, Raja A, Rajalbandi R, Rajani R, Rajasekaran RB, Rajasekaran S, Rajkovic S, Ramirez MT, Ramkumar DB, Rankin KS, Ras El Abiad A, et al. A modified Delphi consensus on tenosynovial giant cell tumour and giant cell tumour of bone : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM). Bone Joint J. 2026 Jun 09; 108-B:1045-1051.
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Gelderblom H, Razak AA, Taylor MH, Bauer TM, Wilky B, Martin-Broto J, Gonzalez AF, Rutkowski P, Szostakowski B, Alcindor T, Saleh R, Genta S, Stacchiotti S, van de Sande M, Wagner AJ, Bernthal N, Davis LE, Vuky J, Tait C, Matin B, Narasimhan S, Sharma MG, Ruiz-Soto R, Sherman ML, Tap WD. CSF1R Inhibition in Patients with Advanced Solid Tumors or Tenosynovial Giant Cell Tumor: A Phase I Study of Vimseltinib. Clin Cancer Res. 2024 Sep 13; 30(18):3996-4004.
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Kao EY, Ardic F, Fadra N, Hohenstein JD, Mopuri R, Wenger DE, Streich L, Hines LM, Folpe AL. Chondroid Synoviocytic Neoplasm: A Clinicopathologic, Immunohistochemical, and Molecular Genetic Study of a Distinctive Tumor of Synoviocytes. Mod Pathol. 2024 11; 37(11):100598.
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Spierenburg G, Staals EL, Palmerini E, Randall RL, Thorpe SW, Wunder JS, Ferguson PC, Verspoor FGM, Houdek MT, Bernthal NM, Schreuder BHWB, Gelderblom H, van de Sande MAJ, van der Heijden L. Active surveillance of diffuse-type tenosynovial giant cell tumors: A retrospective, multicenter cohort study. Eur J Surg Oncol. 2024 02; 50(2):107953.
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Peterfy C, Chen Y, Countryman P, Chmielowski B, Anthony SP, Healey JH, Wainberg ZA, Cohn AL, Shapiro GI, Keedy VL, Singh A, Puzanov I, Wagner AJ, Qian M, Sterba M, Hsu HH, Tong-Starksen S, Tap WD. CSF1 receptor inhibition of tenosynovial giant cell tumor using novel disease-specific MRI measures of tumor burden. Future Oncol. 2022 Apr; 18(12):1449-1459.
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Tap WD, Singh AS, Anthony SP, Sterba M, Zhang C, Healey JH, Chmielowski B, Cohn AL, Shapiro GI, Keedy VL, Wainberg ZA, Puzanov I, Cote GM, Wagner AJ, Braiteh F, Sherman E, Hsu HH, Peterfy C, Gelhorn HL, Ye X, Severson P, West BL, Lin PS, Tong-Starksen S. Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT. Clin Cancer Res. 2022 01 15; 28(2):298-307.
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Smith BD, Kaufman MD, Wise SC, Ahn YM, Caldwell TM, Leary CB, Lu WP, Tan G, Vogeti L, Vogeti S, Wilky BA, Davis LE, Sharma M, Ruiz-Soto R, Flynn DL. Vimseltinib: A Precision CSF1R Therapy for Tenosynovial Giant Cell Tumors and Diseases Promoted by Macrophages. Mol Cancer Ther. 2021 11; 20(11):2098-2109.
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Lin F, Ionescu-Ittu R, Pivneva I, Wynant W, Shi S, Wu EQ, Kwong WJ, Abraham JA. The Economic Burden of Tenosynovial Giant Cell Tumors Among Employed Workforce in the United States. J Occup Environ Med. 2021 04 01; 63(4):e197-e202.
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