 Sarcoma, Alveolar Soft Part
"Sarcoma, Alveolar Soft Part" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A variety of rare sarcoma having a reticulated fibrous stroma enclosing groups of sarcoma cells, which resemble epithelial cells and are enclosed in alveoli walled with connective tissue. It is a rare tumor, usually occurring between 15 and 35 years of age. It appears in the muscles of the extremities in adults and most commonly in the head and neck regions of children. Though slow-growing, it commonly metastasizes to the lungs, brain, bones, and lymph nodes. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1365)
| Descriptor ID |
D018234
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| MeSH Number(s) |
C04.557.450.590.775 C04.557.450.795.775
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sarcoma, Alveolar Soft Part".
Below are MeSH descriptors whose meaning is more specific than "Sarcoma, Alveolar Soft Part".
This graph shows the total number of publications written about "Sarcoma, Alveolar Soft Part" by people in this website by year, and whether "Sarcoma, Alveolar Soft Part" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sarcoma, Alveolar Soft Part" by people in Profiles.
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Wilky BA, Maleddu A. Much Ado about ASPS: The Rapidly Changing Treatment Paradigms of 2022. Clin Cancer Res. 2023 04 03; 29(7):1163-1166.
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Wilky BA, Trucco MM, Subhawong TK, Florou V, Park W, Kwon D, Wieder ED, Kolonias D, Rosenberg AE, Kerr DA, Sfakianaki E, Foley M, Merchan JR, Komanduri KV, Trent JC. Axitinib plus pembrolizumab in patients with advanced sarcomas including alveolar soft-part sarcoma: a single-centre, single-arm, phase 2 trial. Lancet Oncol. 2019 06; 20(6):837-848.
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Kobos R, Nagai M, Tsuda M, Merl MY, Saito T, La? M, Mo Q, Olshen A, Lianoglou S, Leslie C, Ostrovnaya I, Antczak C, Djaballah H, Ladanyi M. Combining integrated genomics and functional genomics to dissect the biology of a cancer-associated, aberrant transcription factor, the ASPSCR1-TFE3 fusion oncoprotein. J Pathol. 2013 Apr; 229(5):743-754.
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Zhong M, De Angelo P, Osborne L, Keane-Tarchichi M, Goldfischer M, Edelmann L, Yang Y, Linehan WM, Merino MJ, Aisner S, Hameed M. Dual-color, break-apart FISH assay on paraffin-embedded tissues as an adjunct to diagnosis of Xp11 translocation renal cell carcinoma and alveolar soft part sarcoma. Am J Surg Pathol. 2010 Jun; 34(6):757-66.
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Aisner SC, Beebe K, Blacksin M, Mirani N, Hameed M. Primary alveolar soft part sarcoma of fibula demonstrating ASPL-TFE3 fusion: a case report and review of the literature. Skeletal Radiol. 2008 Nov; 37(11):1047-51.
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Guntupalli S, Anderson ML, Bodurka DC. Alveolar soft part sarcoma of the cervix: case report and literature review. Arch Gynecol Obstet. 2009 Feb; 279(2):263-5.
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Lillehei KO, Kleinschmidt-DeMasters B, Mitchell DH, Spector E, Kruse CA. Alveolar soft part sarcoma: an unusually long interval between presentation and brain metastasis. Hum Pathol. 1993 Sep; 24(9):1030-4.
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