 Strychnine
"Strychnine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine receptors and thus a convulsant. It has been used as an analeptic, in the treatment of nonketotic hyperglycinemia and sleep apnea, and as a rat poison.
| Descriptor ID |
D013331
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| MeSH Number(s) |
D03.132.436.681.722 D03.633.100.473.402.681.722
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Strychnine".
Below are MeSH descriptors whose meaning is more specific than "Strychnine".
This graph shows the total number of publications written about "Strychnine" by people in this website by year, and whether "Strychnine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Strychnine" by people in Profiles.
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Sargent PB, Saviane C, Nielsen TA, DiGregorio DA, Silver RA. Rapid vesicular release, quantal variability, and spillover contribute to the precision and reliability of transmission at a glomerular synapse. J Neurosci. 2005 Sep 07; 25(36):8173-87.
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Pollak GD, Burger RM, Park TJ, Klug A, Bauer EE. Roles of inhibition for transforming binaural properties in the brainstem auditory system. Hear Res. 2002 Jun; 168(1-2):60-78.
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Bauer EE, Klug A, Pollak GD. Features of contralaterally evoked inhibition in the inferior colliculus. Hear Res. 2000 Mar; 141(1-2):80-96.
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Snell LD, Claffey DJ, Ruth JA, Valenzuela CF, Cardoso R, Wang Z, Levinson SR, Sather WA, Williamson AV, Ingersoll NC, Ovchinnikova L, Bhave SV, Hoffman PL, Tabakoff B. Novel structure having antagonist actions at both the glycine site of the N-methyl-D-aspartate receptor and neuronal voltage-sensitive sodium channels: biochemical, electrophysiological, and behavioral characterization. J Pharmacol Exp Ther. 2000 Jan; 292(1):215-27.
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Klug A, Park TJ, Pollak GD. Glycine and GABA influence binaural processing in the inferior colliculus of the mustache bat. J Neurophysiol. 1995 Oct; 74(4):1701-13.
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Tauck DL, Ashbeck GA. Glycine synergistically potentiates the enhancement of LTP induced by a sulfhydryl reducing agent. Brain Res. 1990 Jun 11; 519(1-2):129-32.
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Kaess A, Mathis C. [Test of pharmaceutical preparations by functional thin-layer chromatography. 3. Preparations containing alkaloids of the strychnine, emetine and lobeline groups]. Ann Pharm Fr. 1966 Dec; 24(12):753-62.
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