 Vinca Alkaloids
"Vinca Alkaloids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.
| Descriptor ID |
D014748
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| MeSH Number(s) |
D03.132.436.681.827 D03.633.100.473.402.681.827
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Vinca Alkaloids".
Below are MeSH descriptors whose meaning is more specific than "Vinca Alkaloids".
This graph shows the total number of publications written about "Vinca Alkaloids" by people in this website by year, and whether "Vinca Alkaloids" was a major or minor topic of these publications.
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Below are the most recent publications written about "Vinca Alkaloids" by people in Profiles.
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Lyle MA, Fenstad ER, McGoon MD, Frantz RP, Krowka MJ, Kane GC, Swanson KL. Pulmonary Hypertension in Hereditary Hemorrhagic Telangiectasia. Chest. 2016 Feb; 149(2):362-371.
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Cai Y, Knight WE, Guo S, Li JD, Knight PA, Yan C. Vinpocetine suppresses pathological vascular remodeling by inhibiting vascular smooth muscle cell proliferation and migration. J Pharmacol Exp Ther. 2012 Nov; 343(2):479-88.
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McDaniel MA, Maier SF, Einstein GO. "Brain-specific" nutrients: a memory cure? Nutrition. 2003 Nov-Dec; 19(11-12):957-75.
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I?iguez C, Larrod? P, Mayordomo JI, Mauri JA, Tr?s A, Morales F. [Peripheral nervous system neurotoxicity secondary to chemotherapy treatment] . Neurologia. 2000 Oct; 15(8):343-51.
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Hoof T, Demmer A, Christians U, T?mmler B. Reversal of multidrug resistance in Chinese hamster ovary cells by the immunosuppressive agent rapamycin. Eur J Pharmacol. 1993 Jun 15; 246(1):53-8.
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Bunn PA, Shackney SE, Ford SS. The effects of colcemid on hematopoiesis in the mouse. J Clin Invest. 1976 Nov; 58(5):1280-5.
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