 Pregnenolone
"Pregnenolone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.
| Descriptor ID |
D011284
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| MeSH Number(s) |
D04.210.500.745.745.725 D06.472.040.585.745 D06.472.334.851.687.500
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| Concept/Terms |
Pregnenolone- Pregnenolone
- 5-Pregnen-3-beta-ol-20-one
- 5 Pregnen 3 beta ol 20 one
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Below are MeSH descriptors whose meaning is more general than "Pregnenolone".
Below are MeSH descriptors whose meaning is more specific than "Pregnenolone".
This graph shows the total number of publications written about "Pregnenolone" by people in this website by year, and whether "Pregnenolone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Pregnenolone" by people in Profiles.
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Schedel M, Jia Y, Michel S, Takeda K, Domenico J, Joetham A, Ning F, Strand M, Han J, Wang M, Lucas JJ, Vogelberg C, Kabesch M, O'Connor BP, Gelfand EW. 1,25D3 prevents CD8(+)Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter. Nat Commun. 2016 Jan 11; 7:10213.
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Jia Y, Domenico J, Takeda K, Han J, Wang M, Armstrong M, Reisdorph N, O'Connor BP, Lucas JJ, Gelfand EW. Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease. Proc Natl Acad Sci U S A. 2013 May 14; 110(20):8152-7.
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Porcello DM, Huntsman MM, Mihalek RM, Homanics GE, Huguenard JR. Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit. J Neurophysiol. 2003 Mar; 89(3):1378-86.
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Kramer RE, Greiner JW, Colby HD. Relation of the pituitary gland to gonadal hormone effects on the adrenocortical 11beta-hydroxylase system in rats. Steroids. 1975 Jun; 25(6):707-16.
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