17-Hydroxycorticosteroids
"17-Hydroxycorticosteroids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of hydroxycorticosteroids bearing a hydroxy group at the 17-position. Urinary excretion of these compounds is used as an index of adrenal function. They are used systemically in the free alcohol form, but with esterification of the hydroxy groups, topical effectiveness is increased.
Descriptor ID |
D015065
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MeSH Number(s) |
D06.472.040.585.478
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "17-Hydroxycorticosteroids".
Below are MeSH descriptors whose meaning is more specific than "17-Hydroxycorticosteroids".
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Below are the most recent publications written about "17-Hydroxycorticosteroids" by people in Profiles.
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Altman LC, Findlay SR, Lopez M, Lukacsko P, Morris RJ, Pinnas JL, Ratner PH, Szefler SJ, Welch MJ. Adrenal function in adult asthmatics during long-term daily treatment with 800, 1,200, and 1,600 micrograms triamcinolone acetonide. Multicenter study. Chest. 1992 May; 101(5):1250-6.
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Weston WL, Fennessey PV, Morelli J, Schwab H, Mooney J, Samson C, Huff L, Harrison LM, Gotlin R. Comparison of hypothalamus-pituitary-adrenal axis suppression from superpotent topical steroids by standard endocrine function testing and gas chromatographic mass spectrometry. J Invest Dermatol. 1988 Apr; 90(4):532-5.
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Pike AW, Klein JL, Gotlin RW, Fennessey PV. The role of steroid metabolic profiling as an aid in the diagnosis of familial precocious puberty, a subgroup of true precocious puberty. J Inherit Metab Dis. 1986; 9(2):147-55.
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Tabakoff B, Yanai J. Cortexolone antagonizes development of alcohol tolerance in mice. Psychopharmacology (Berl). 1979 Jun 28; 64(1):123-4.
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Hagen GA, Bolman RM, Frank JP. Atypical adrenal insufficiency with failure of the pituitary feedback receptor. A case with associated diabetes mellitus and selective IgA deficiency with steatorrhea. Am J Med. 1975 Dec; 59(6):882-8.
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