Angiostatins
"Angiostatins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Circulating 38-kDa proteins that are internal peptide fragments of PLASMINOGEN. The name derives from the fact that they are potent ANGIOGENESIS INHIBITORS. Angiostatins contain four KRINGLE DOMAINS which are associated with their potent angiostatic activity.
Descriptor ID |
D043168
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MeSH Number(s) |
D08.622.610.500 D12.644.276.100.450.500 D12.776.124.790.223.580.500 D12.776.377.715.182.580.500 D12.776.467.100.450.500 D23.529.100.450.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Angiostatins".
Below are MeSH descriptors whose meaning is more specific than "Angiostatins".
This graph shows the total number of publications written about "Angiostatins" by people in this website by year, and whether "Angiostatins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 0 | 1 | 2008 | 1 | 0 | 1 | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Angiostatins" by people in Profiles.
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Barrett CD, Moore HB, Banerjee A, Silliman CC, Moore EE, Yaffe MB. Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin. J Trauma Acute Care Surg. 2017 12; 83(6):1053-1061.
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Mu W, Long DA, Ouyang X, Agarwal A, Cruz PE, Roncal CA, Nakagawa T, Yu X, Hauswirth WW, Johnson RJ. Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism. Am J Physiol Renal Physiol. 2009 Jan; 296(1):F145-52.
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Raikwar SP, Temm CJ, Raikwar NS, Kao C, Molitoris BA, Gardner TA. Adenoviral vectors expressing human endostatin-angiostatin and soluble Tie2: enhanced suppression of tumor growth and antiangiogenic effects in a prostate tumor model. Mol Ther. 2005 Dec; 12(6):1091-100.
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