4-Hydroxycoumarins
"4-Hydroxycoumarins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances found in many plants, containing the 4-hydroxycoumarin radical. They interfere with vitamin K and the blood clotting mechanism, are tightly protein-bound, inhibit mitochondrial and microsomal enzymes, and are used as oral anticoagulants.
Descriptor ID |
D015110
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MeSH Number(s) |
D03.383.663.283.446.520 D03.633.100.150.446.520
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "4-Hydroxycoumarins".
Below are MeSH descriptors whose meaning is more specific than "4-Hydroxycoumarins".
This graph shows the total number of publications written about "4-Hydroxycoumarins" by people in this website by year, and whether "4-Hydroxycoumarins" was a major or minor topic of these publications.
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Below are the most recent publications written about "4-Hydroxycoumarins" by people in Profiles.
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Franklin AB, Carlson PC, Rex A, Rockweit JT, Garza D, Culhane E, Volker SF, Dusek RJ, Shearn-Bochsler VI, Gabriel MW, Horak KE. Grass is not always greener: rodenticide exposure of a threatened species near marijuana growing operations. BMC Res Notes. 2018 Feb 02; 11(1):94.
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Anderson SL, Kattappuram RS, Marrs JC, Joseph NM. Intentional Brodifacoum Ingestion. Am J Med. 2017 Jan; 130(1):e27-e28.
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Nolan KA, Doncaster JR, Dunstan MS, Scott KA, Frenkel AD, Siegel D, Ross D, Barnes J, Levy C, Leys D, Whitehead RC, Stratford IJ, Bryce RA. Synthesis and biological evaluation of coumarin-based inhibitors of NAD(P)H: quinone oxidoreductase-1 (NQO1). J Med Chem. 2009 Nov 26; 52(22):7142-56.
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La Rosa FG, Clarke SH, Lefkowitz JB. Brodifacoum intoxication with marijuana smoking. Arch Pathol Lab Med. 1997 Jan; 121(1):67-9.
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Smolinske SC, Scherger DL, Kearns PS, Wruk KM, Kulig KW, Rumack BH. Superwarfarin poisoning in children: a prospective study. Pediatrics. 1989 Sep; 84(3):490-4.
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