Oligomycins
"Oligomycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A closely related group of toxic substances elaborated by various strains of Streptomyces. They are 26-membered macrolides with lactone moieties and double bonds and inhibit various ATPases, causing uncoupling of phosphorylation from mitochondrial respiration. Used as tools in cytochemistry. Some specific oligomycins are RUTAMYCIN, peliomycin, and botrycidin (formerly venturicidin X).
Descriptor ID |
D009840
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MeSH Number(s) |
D02.540.505.620
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Oligomycins".
Below are MeSH descriptors whose meaning is more specific than "Oligomycins".
This graph shows the total number of publications written about "Oligomycins" by people in this website by year, and whether "Oligomycins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Oligomycins" by people in Profiles.
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Alvarez-Calderon F, Gregory MA, Pham-Danis C, DeRyckere D, Stevens BM, Zaberezhnyy V, Hill AA, Gemta L, Kumar A, Kumar V, Wempe MF, Pollyea DA, Jordan CT, Serkova NJ, Graham DK, DeGregori J. Tyrosine kinase inhibition in leukemia induces an altered metabolic state sensitive to mitochondrial perturbations. Clin Cancer Res. 2015 Mar 15; 21(6):1360-72.
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Van Blerkom J, Davis P, Alexander S. Inner mitochondrial membrane potential (DeltaPsim), cytoplasmic ATP content and free Ca2+ levels in metaphase II mouse oocytes. Hum Reprod. 2003 Nov; 18(11):2429-40.
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Nobes CD, Hay WW, Brand MD. The mechanism of stimulation of respiration by fatty acids in isolated hepatocytes. J Biol Chem. 1990 Aug 05; 265(22):12910-5.
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Klymkowsky MW. Metabolic inhibitors and intermediate filament organization in human fibroblasts. Exp Cell Res. 1988 Jan; 174(1):282-90.
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