 Axoneme
"Axoneme" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bundle of MICROTUBULES and MICROTUBULE-ASSOCIATED PROTEINS forming the core of each CILIUM or FLAGELLUM. In most eukaryotic cilia or flagella, an axoneme shaft has 20 microtubules arranged in nine doublets and two singlets.
| Descriptor ID |
D054468
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| MeSH Number(s) |
A11.284.430.214.190.750.602.309
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Axoneme".
Below are MeSH descriptors whose meaning is more specific than "Axoneme".
This graph shows the total number of publications written about "Axoneme" by people in this website by year, and whether "Axoneme" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Axoneme" by people in Profiles.
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Ceglowski J, Hoffman HK, Neumann AJ, Hoff KJ, McCurdy BL, Moore JK, Prekeris R. TTLL12 is required for primary ciliary axoneme formation in polarized epithelial cells. EMBO Rep. 2024 Jan; 25(1):198-227.
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Fabritius AS, Bayless BA, Li S, Stoddard D, Heydeck W, Ebmeier CC, Anderson L, Gunnels T, Nachiappan C, Whittall JB, Old W, Agard DA, Nicastro D, Winey M. Proteomic analysis of microtubule inner proteins (MIPs) in Rib72 null Tetrahymena cells reveals functional MIPs. Mol Biol Cell. 2021 11 01; 32(21):br8.
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Richard McIntosh J, O'Toole E, Page C, Morgan G. Ultrastructural Analysis of Microtubule Ends. Methods Mol Biol. 2020; 2101:191-209.
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Lin J, Le TV, Augspurger K, Tritschler D, Bower R, Fu G, Perrone C, O'Toole ET, Mills KV, Dymek E, Smith E, Nicastro D, Porter ME. FAP57/WDR65 targets assembly of a subset of inner arm dyneins and connects to regulatory hubs in cilia. Mol Biol Cell. 2019 10 01; 30(21):2659-2680.
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H??g JL, Lacomble S, Bouchet-Marquis C, Briggs L, Park K, Hoenger A, Gull K. 3D Architecture of the Trypanosoma brucei Flagella Connector, a Mobile Transmembrane Junction. PLoS Negl Trop Dis. 2016 Jan; 10(1):e0004312.
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Yang F, Pavlik J, Fox L, Scarbrough C, Sale WS, Sisson JH, Wirschell M. Alcohol-induced ciliary dysfunction targets the outer dynein arm. Am J Physiol Lung Cell Mol Physiol. 2015 Mar 15; 308(6):L569-76.
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H??g JL, Lacomble S, O'Toole ET, Hoenger A, McIntosh JR, Gull K. Modes of flagellar assembly in Chlamydomonas reinhardtii and Trypanosoma brucei. Elife. 2014; 3:e01479.
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Knowles MR, Ostrowski LE, Loges NT, Hurd T, Leigh MW, Huang L, Wolf WE, Carson JL, Hazucha MJ, Yin W, Davis SD, Dell SD, Ferkol TW, Sagel SD, Olivier KN, Jahnke C, Olbrich H, Werner C, Raidt J, Wallmeier J, Pennekamp P, Dougherty GW, Hjeij R, Gee HY, Otto EA, Halbritter J, Chaki M, Diaz KA, Braun DA, Porath JD, Schueler M, Baktai G, Griese M, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Omran H, Zariwala MA. Mutations in SPAG1 cause primary ciliary dyskinesia associated with defective outer and inner dynein arms. Am J Hum Genet. 2013 Oct 03; 93(4):711-20.
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Yamamoto R, Song K, Yanagisawa HA, Fox L, Yagi T, Wirschell M, Hirono M, Kamiya R, Nicastro D, Sale WS. The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility. J Cell Biol. 2013 Apr 15; 201(2):263-78.
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Bower R, Tritschler D, Vanderwaal K, Perrone CA, Mueller J, Fox L, Sale WS, Porter ME. The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes. Mol Biol Cell. 2013 Apr; 24(8):1134-52.
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