 Anesthetics, General
"Anesthetics, General" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that induce various degrees of analgesia; depression of consciousness, circulation, and respiration; relaxation of skeletal muscle; reduction of reflex activity; and amnesia. There are two types of general anesthetics, inhalation and intravenous. With either type, the arterial concentration of drug required to induce anesthesia varies with the condition of the patient, the desired depth of anesthesia, and the concomitant use of other drugs. (From AMA Drug Evaluations Annual, 1994, p.173)
| Descriptor ID |
D018681
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| MeSH Number(s) |
D27.505.696.277.100.035 D27.505.954.427.210.100.035
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Anesthetics, General".
Below are MeSH descriptors whose meaning is more specific than "Anesthetics, General".
This graph shows the total number of publications written about "Anesthetics, General" by people in this website by year, and whether "Anesthetics, General" was a major or minor topic of these publications.
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Below are the most recent publications written about "Anesthetics, General" by people in Profiles.
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Timic Stamenic T, Todorovic SM. Thalamic T-Type Calcium Channels as Targets for Hypnotics and General Anesthetics. Int J Mol Sci. 2022 Feb 21; 23(4).
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Maksimovic S, Useinovic N, Quillinan N, Covey DF, Todorovic SM, Jevtovic-Todorovic V. General Anesthesia and the Young Brain: The Importance of Novel Strategies with Alternate Mechanisms of Action. Int J Mol Sci. 2022 Feb 08; 23(3).
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Jevtovic-Todorovic V. Sex hormones and the young brain: are we ready to embrace neuroprotective strategies? Br J Anaesth. 2022 02; 128(2):229-231.
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Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW, Ma D, Orser BA, Planel E, Slikker W, Soriano SG, Stratmann G, Vutskits L, Xie Z, Hemmings HC. Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar. Br J Anaesth. 2013 Aug; 111(2):143-51.
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Boscolo A, Ori C, Bennett J, Wiltgen B, Jevtovic-Todorovic V. Mitochondrial protectant pramipexole prevents sex-specific long-term cognitive impairment from early anaesthesia exposure in rats. Br J Anaesth. 2013 Jun; 110 Suppl 1:i47-52.
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Jevtovic-Todorovic V. Developmental synaptogenesis and general anesthesia: a kiss of death? Curr Pharm Des. 2012; 18(38):6225-31.
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Sanchez V, Feinstein SD, Lunardi N, Joksovic PM, Boscolo A, Todorovic SM, Jevtovic-Todorovic V. General Anesthesia Causes Long-term Impairment of Mitochondrial Morphogenesis and Synaptic Transmission in Developing Rat Brain. Anesthesiology. 2011 Nov; 115(5):992-1002.
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Orestes P, Todorovic SM. Are neuronal voltage-gated calcium channels valid cellular targets for general anesthetics? Channels (Austin). 2010 Nov-Dec; 4(6):518-22.
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Joksovic PM, Brimelow BC, Murbarti?n J, Perez-Reyes E, Todorovic SM. Contrasting anesthetic sensitivities of T-type Ca2+ channels of reticular thalamic neurons and recombinant Ca(v)3.3 channels. Br J Pharmacol. 2005 Jan; 144(1):59-70.
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Visweswaraiah A, Novotny LA, Hjemdahl-Monsen EJ, Bakaletz LO, Thanavala Y. Tracking the tissue distribution of marker dye following intranasal delivery in mice and chinchillas: a multifactorial analysis of parameters affecting nasal retention. Vaccine. 2002 Aug 19; 20(25-26):3209-20.
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