 Anesthetics, Local
"Anesthetics, Local" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
| Descriptor ID |
D000779
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| MeSH Number(s) |
D27.505.696.277.100.200 D27.505.696.663.850.025 D27.505.954.427.210.100.200
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| Concept/Terms |
Anesthetics, Local- Anesthetics, Local
- Local Anesthetics
- Conduction-Blocking Anesthetics
- Conduction Blocking Anesthetics
- Anesthetics, Conduction-Blocking
- Anesthetics, Conduction Blocking
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Below are MeSH descriptors whose meaning is more general than "Anesthetics, Local".
Below are MeSH descriptors whose meaning is more specific than "Anesthetics, Local".
This graph shows the total number of publications written about "Anesthetics, Local" by people in this website by year, and whether "Anesthetics, Local" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 1999 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 2 | 3 | | 2008 | 0 | 1 | 1 | | 2010 | 1 | 2 | 3 | | 2011 | 3 | 2 | 5 | | 2012 | 1 | 3 | 4 | | 2013 | 2 | 1 | 3 | | 2014 | 3 | 3 | 6 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 1 | 2 | | 2017 | 3 | 2 | 5 | | 2018 | 4 | 3 | 7 | | 2019 | 1 | 0 | 1 | | 2020 | 2 | 2 | 4 | | 2021 | 0 | 3 | 3 | | 2022 | 1 | 3 | 4 | | 2023 | 2 | 2 | 4 |
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Below are the most recent publications written about "Anesthetics, Local" by people in Profiles.
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Webster A, Pezzanite L, Hendrickson D, Griffenhagen G. Review of intra-articular local anaesthetic administration in horses: Clinical indications, cytotoxicity, and outcomes. Equine Vet J. 2024 Sep; 56(5):870-883.
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Sulewski M, Leslie L, Liu SH, Ifantides C, Cho K, Kuo IC. Topical ophthalmic anesthetics for corneal abrasions. Cochrane Database Syst Rev. 2023 08 09; 8:CD015091.
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Nguyen L, Glassman GE, Afshari A, Feng X, Shastri UD, Kaoutzanis C, McEvoy MD, Bansal V, Canlas C, Yao J, Higdon K, Perdikis G. Randomized Controlled Trial Comparing Liposomal to Plain Bupivacaine in the Transversus Abdominis Plane for DIEP Flap Breast Reconstruction. Plast Reconstr Surg. 2024 03 01; 153(3):543-551.
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Pezzanite LM, Griffenhagen GM, Bass L, Okudaira M, Larson B, Hendrickson DA. Liposomal bupivacaine is both safe and effective when administered via local infiltration at surgical site and mesovarium for laparoscopic ovariectomy in mares. Equine Vet J. 2023 Sep; 55(5):755-764.
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Lamira JM, Wilson CS, Leppek NC, Orr CM, De la Rosa LM, Greany TJ. A pilot study of local anesthesia training using a mixed-reality haptic fidelity model. J Dent Educ. 2023 Apr; 87(4):583-591.
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Masaracchia MM, Zaretsky MV, Pan Z, Zhou W, Chow FS, Wood CL. Evolution of postoperative care: marked reduction of opioid consumption when ERAC pathway added to wound soaker therapy for cesarean delivery. J Matern Fetal Neonatal Med. 2023 Dec; 36(1):2130241.
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Berg AA, Flaherty JM, Habeck JM, Harrison AK, Braman JP, Kaizer AM, Hutchins JL. Evaluation of Diaphragmatic Function after Interscalene Block with Liposomal Bupivacaine: A Randomized Controlled Trial. Anesthesiology. 2022 04 01; 136(4):531-541.
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Flaherty JM, Berg AA, Harrison A, Braman J, Pearson JM, Matelich B, Kaizer AM, Hutchins JL. Comparing liposomal bupivacaine plus bupivacaine to bupivacaine alone in interscalene blocks for rotator cuff repair surgery: a randomized clinical trial. Reg Anesth Pain Med. 2022 05; 47(5):309-312.
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Cralley AL, Hopman J, Leasia K, Robinson C, Morton A, Pieracci FM. Earlier liposomal bupivacaine blocks improve analgesia and decrease opioid requirements for bariatric surgery patients. Am J Surg. 2022 07; 224(1 Pt A):75-79.
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Davidson RS, Donaldson K, Jeffries M, Khandelwal S, Raizman M, Rodriguez Torres Y, Kim T. Persistent opioid use in cataract surgery pain management and the role of nonopioid alternatives. J Cataract Refract Surg. 2022 06 01; 48(6):730-740.
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