 Apomorphine
"Apomorphine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use.
| Descriptor ID |
D001058
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| MeSH Number(s) |
D03.132.098.038.290 D03.633.100.531.085.030.290 D03.633.400.095.290
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| Concept/Terms |
Apomorphine Hydrochloride, Anhydrous- Apomorphine Hydrochloride, Anhydrous
- Anhydrous Apomorphine Hydrochloride
- Hydrochloride, Anhydrous Apomorphine
- Apomorphine Hydrochloride Anhydrous
- Anhydrous, Apomorphine Hydrochloride
- Hydrochloride Anhydrous, Apomorphine
Apomorphine Hydrochloride- Apomorphine Hydrochloride
- Hydrochloride, Apomorphine
- Apomorphine Hydrochloride, Hemihydrate
- Hemihydrate Apomorphine Hydrochloride
- Hydrochloride, Hemihydrate Apomorphine
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Below are MeSH descriptors whose meaning is more general than "Apomorphine".
Below are MeSH descriptors whose meaning is more specific than "Apomorphine".
This graph shows the total number of publications written about "Apomorphine" by people in this website by year, and whether "Apomorphine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Apomorphine" by people in Profiles.
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Gunzler SA, Pavel M, Koudelka C, Carlson NE, Nutt JG. Foot-tapping rate as an objective outcome measure for Parkinson disease clinical trials. Clin Neuropharmacol. 2009 Mar-Apr; 32(2):97-102.
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Gunzler SA, Koudelka C, Carlson NE, Pavel M, Nutt JG. Effect of low concentrations of apomorphine on parkinsonism in a randomized, placebo-controlled, crossover study. Arch Neurol. 2008 Feb; 65(2):193-8.
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Gunzler SA, Shakil S, Carlson NE, Nutt JG, Meshul CK. Low doses of apomorphine transiently reduce locomotor activity in MPTP-treated mice. Neurosci Lett. 2007 Nov 27; 428(2-3):64-7.
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Swerdlow NR, Geyer MA, Shoemaker JM, Light GA, Braff DL, Stevens KE, Sharp R, Breier M, Neary A, Auerbach PP. Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and N40 suppression in rats. Neuropsychopharmacology. 2006 Mar; 31(3):506-15.
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Clarkson ED, Zawada WM, Bell KP, Esplen JE, Choi PK, Heidenreich KA, Freed CR. IGF-I and bFGF improve dopamine neuron survival and behavioral outcome in parkinsonian rats receiving cultured human fetal tissue strands. Exp Neurol. 2001 Mar; 168(1):183-91.
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Palmer MR, Granholm AC, van Horne CG, Giardina KE, Freund RK, Moorhead JW, Gerhardt GA. Intranigral transplantation of solid tissue ventral mesencephalon or striatal grafts induces behavioral recovery in 6-OHDA-lesioned rats. Brain Res. 2001 Jan 26; 890(1):86-99.
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Kuprys R, Tabakoff B. Prenatal phenobarbital treatment and temperature-controlling dopamine receptors. Pharmacol Biochem Behav. 1983 Mar; 18(3):401-6.
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Black RF, Hoffman PL, Tabakoff B. Receptor-mediated dopaminergic function after ethanol withdrawal. Alcohol Clin Exp Res. 1980 Jul; 4(3):294-7.
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Tabakoff B, Black RF. A high performance liquid chromatography method for measuring brain dihydroxyphenylalanine levels and dopamine synthesis rates. J Neurochem. 1980 Jun; 34(6):1707-11.
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Hoffman PL, Tabakoff B. Adaptive changes in the dopamine system produced by chronic ethanol feeding. Drug Alcohol Depend. 1979 May-Jul; 4(3-4):255-60.
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