 Thrombin Time
"Thrombin Time" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin.
| Descriptor ID |
D013918
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| MeSH Number(s) |
E01.370.225.625.115.870 E05.200.625.115.870 G09.188.840
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| Concept/Terms |
Thrombin Time- Thrombin Time
- Thrombin Times
- Time, Thrombin
- Times, Thrombin
- Reptilase Time
- Reptilase Times
- Time, Reptilase
- Times, Reptilase
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Below are MeSH descriptors whose meaning is more general than "Thrombin Time".
Below are MeSH descriptors whose meaning is more specific than "Thrombin Time".
This graph shows the total number of publications written about "Thrombin Time" by people in this website by year, and whether "Thrombin Time" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thrombin Time" by people in Profiles.
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Beyer JT, Lind SE, Fisher S, Trujillo TC, Wempe MF, Kiser TH. Evaluation of intravenous direct thrombin inhibitor monitoring tests: Correlation with plasma concentrations and clinical outcomes in hospitalized patients. J Thromb Thrombolysis. 2020 Feb; 49(2):259-267.
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Kumar P, Gordon LA, Brooks KM, George JM, Kellogg A, McManus M, Alfaro RM, Nghiem K, Lozier J, Hadigan C, Penzak SR. Differential Influence of the Antiretroviral Pharmacokinetic Enhancers Ritonavir and Cobicistat on Intestinal P-Glycoprotein Transport and the Pharmacokinetic/Pharmacodynamic Disposition of Dabigatran. Antimicrob Agents Chemother. 2017 11; 61(11).
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Gordon LA, Kumar P, Brooks KM, Kellogg A, McManus M, Alfaro RM, Nghiem K, George JM, Lozier J, Penzak SR, Hadigan C. Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers. Circulation. 2016 12 06; 134(23):1909-1911.
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Lind SE, Boyle ME, Fisher S, Ishimoto J, Trujillo TC, Kiser TH. Comparison of the aPTT with alternative tests for monitoring direct thrombin inhibitors in patient samples. Am J Clin Pathol. 2014 May; 141(5):665-74.
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Walter S, Stabler S, Lefkowitz JB. Fibrinogen Denver: a dysfibrinogenemia associated with an abnormal Reptilase time and significant bleeding. Haemophilia. 2006 Jul; 12(4):393-7.
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Fasules JW, Stenmark KR, Henson PM, Voelkel NF, Reeves JT. Neither anticoagulant nor nonanticoagulant heparin affects monocrotaline lung injury. J Appl Physiol (1985). 1987 Feb; 62(2):816-20.
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