Partial Thromboplastin Time
"Partial Thromboplastin Time" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy.
Descriptor ID |
D010314
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MeSH Number(s) |
E01.370.225.625.115.600 E05.200.625.115.600 G09.188.660
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Concept/Terms |
Kaolin-Cephalin Coagulation Time- Kaolin-Cephalin Coagulation Time
- Coagulation Time, Kaolin-Cephalin
- Kaolin Cephalin Coagulation Time
- Coagulation Time, Cephalin-Kaolin
- Coagulation Time, Cephalin Kaolin
- Cephalin-Kaolin Coagulation Time
- Cephalin Kaolin Coagulation Time
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Below are MeSH descriptors whose meaning is more general than "Partial Thromboplastin Time".
Below are MeSH descriptors whose meaning is more specific than "Partial Thromboplastin Time".
This graph shows the total number of publications written about "Partial Thromboplastin Time" by people in this website by year, and whether "Partial Thromboplastin Time" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 1997 | 1 | 2 | 3 | 1998 | 0 | 1 | 1 | 2002 | 1 | 1 | 2 | 2003 | 0 | 3 | 3 | 2005 | 0 | 2 | 2 | 2006 | 0 | 2 | 2 | 2008 | 0 | 2 | 2 | 2011 | 0 | 2 | 2 | 2012 | 0 | 2 | 2 | 2014 | 2 | 1 | 3 | 2019 | 0 | 3 | 3 | 2020 | 0 | 1 | 1 | 2021 | 0 | 2 | 2 | 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Partial Thromboplastin Time" by people in Profiles.
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Buckley MS, Benanti GE, Gilbert B, Meckel J, Dzierba AL, MacLaren R. Correlation between heparin anti-Xa activity and thromboelastography in adult critically ill COVID-19 patients. Pharmacotherapy. 2023 08; 43(8):795-803.
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Buckley MS, Benanti GE, Meckel J, Tekle LA, Gilbert B, Puebla Neira D, McNierney DA, Korkames G, Yerondopoulos M, Park A, O'Hea JA, MacLaren R. Correlation between partial thromboplastin time and thromboelastography in adult critically ill patients requiring bivalirudin for extracorporeal membrane oxygenation. Pharmacotherapy. 2023 03; 43(3):196-204.
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Swayngim R, Preslaski C, Burlew CC, Beyer J. Comparison of clinical outcomes using activated partial thromboplastin time versus antifactor-Xa for monitoring therapeutic unfractionated heparin: A systematic review and meta-analysis. Thromb Res. 2021 Dec; 208:18-25.
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Barrett CD, Moore HB, Moore EE, Wang J, Hajizadeh N, Biffl WL, Lottenberg L, Patel PR, Truitt MS, McIntyre RC, Bull TM, Ammons LA, Ghasabyan A, Chandler J, Douglas IS, Schmidt EP, Moore PK, Wright FL, Ramdeo R, Borrego R, Rueda M, Dhupa A, McCaul DS, Dandan T, Sarkar PK, Khan B, Sreevidya C, McDaniel C, Grossman Verner HM, Pearcy C, Anez-Bustillos L, Baedorf-Kassis EN, Jhunjhunwala R, Shaefi S, Capers K, Banner-Goodspeed V, Talmor DS, Sauaia A, Yaffe MB. Study of Alteplase for Respiratory Failure in SARS-CoV-2 COVID-19: A Vanguard Multicenter, Rapidly Adaptive, Pragmatic, Randomized Controlled Trial. Chest. 2022 03; 161(3):710-727.
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Wright FL, Vogler TO, Moore EE, Moore HB, Wohlauer MV, Urban S, Nydam TL, Moore PK, McIntyre RC. Fibrinolysis Shutdown Correlation with Thromboembolic Events in Severe COVID-19 Infection. J Am Coll Surg. 2020 08; 231(2):193-203.e1.
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Stettler GR, Moore EE, Moore HB, Nunns GR, Coleman JR, Colvis A, Ghasabyan A, Cohen MJ, Silliman CC, Banerjee A, Sauaia A. Variability in international normalized ratio and activated partial thromboplastin time after injury are not explained by coagulation factor deficits. J Trauma Acute Care Surg. 2019 09; 87(3):582-589.
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Gitomer SA, Shebha Anand G, Bradley HE, Kumar M, Ouellette L, Musso MF. Screening for undiagnosed bleeding disorders in post-tonsillectomy bleed patients: Retrospective review and systematic review of the literature. Int J Pediatr Otorhinolaryngol. 2019 Sep; 124:210-214.
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Sumislawski JJ, Christie SA, Kornblith LZ, Stettler GR, Nunns GR, Moore HB, Moore EE, Silliman CC, Sauaia A, Callcut RA, Cohen MJ. Discrepancies between conventional and viscoelastic assays in identifying trauma-induced coagulopathy. Am J Surg. 2019 06; 217(6):1037-1041.
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Richardson R, Todd JM, Sharkey LC, Washabau RJ, Williams KD, Little KJ, Rendahl A. Retrospective characterization of canine coagulopathies using the turbidimetric ACL-TOP 300 analyzer (2014-2015): Forty-seven dogs. J Vet Emerg Crit Care (San Antonio). 2018 Nov; 28(6):551-558.
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Sharkey LC, Little KJ, Williams KD, Todd JM, Richardson R, Gwynn AD, Rendahl A. Performance characteristics of the turbidimetric ACL-TOP CTS 300 coagulation analyzer in dogs and cats. J Vet Emerg Crit Care (San Antonio). 2018 Jul; 28(4):317-325.
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