A nonspecific term referring both to the pathologic finding of swelling of distal portions of axons in the brain and to disorders which feature this finding. Neuroaxonal dystrophy is seen in various genetic diseases, vitamin deficiencies, and aging. Infantile neuroaxonal dystrophy is an autosomal recessive disease characterized by arrested psychomotor development at 6 months to 2 years of age, ataxia, brain stem dysfunction, and quadriparesis. Juvenile and adult forms also occur. Pathologic findings include brain atrophy and widespread accumulation of axonal spheroids throughout the neuroaxis, peripheral nerves, and dental pulp. (From Davis & Robertson, Textbook of Neuropathology, 2nd ed, p927)

Descriptor ID	D019150
MeSH Number(s)	C10.228.140.744
Concept/Terms	Neuroaxonal Dystrophies Neuroaxonal Dystrophies Dystrophy, Neuroaxonal Neuroaxonal Dystrophy NBIA2A Late Infantile Neuroaxonal Dystrophy Late Infantile Neuroaxonal Dystrophy Neuroaxonal Dystrophy, Late Infantile Juvenile Neuroaxonal Dystrophy Juvenile Neuroaxonal Dystrophy Dystrophy, Juvenile Neuroaxonal Neuroaxonal Dystrophy, Juvenile Adult Neuroaxonal Dystrophy Adult Neuroaxonal Dystrophy Dystrophy, Adult Neuroaxonal Neuroaxonal Dystrophy, Adult Infantile Neuroaxonal Dystrophy Infantile Neuroaxonal Dystrophy Dystrophy, Infantile Neuroaxonal Neuroaxonal Dystrophy, Infantile Seitelberger's Disease Disease, Seitelberger's Seitelbergers Disease Neurodegeneration, PLA2G6-Associated Neurodegeneration, PLA2G6 Associated PLA2G6-Associated Neurodegeneration Seitelberger Disease Disease, Seitelberger NBIA, PLA2G6-Related NBIA, PLA2G6 Related PLA2G6-Related NBIA Neurodegeneration With Brain Iron Accumulation 2A

Below are MeSH descriptors whose meaning is more general than "Neuroaxonal Dystrophies".

Below are MeSH descriptors whose meaning is related to "Neuroaxonal Dystrophies".

Below are MeSH descriptors whose meaning is more specific than "Neuroaxonal Dystrophies".