Bryostatins
"Bryostatins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of 20-member macrolactones in which there are three remotely substituted pyran rings that are linked by a methylene bridge and an E-disubstituted alkene, and have geminal dimethyls at C8 and C18 carbons. Some interact with PROTEIN KINASE C.
Descriptor ID |
D054713
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MeSH Number(s) |
D02.540.576.500.937
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Bryostatins".
Below are MeSH descriptors whose meaning is more specific than "Bryostatins".
This graph shows the total number of publications written about "Bryostatins" by people in this website by year, and whether "Bryostatins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bryostatins" by people in Profiles.
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Li BX, Zhang H, Liu Y, Li Y, Zheng JJ, Li WX, Feng K, Sun M, Dai SX. Novel pathways of HIV latency reactivation revealed by integrated analysis of transcriptome and target profile of bryostatin. Sci Rep. 2020 02 26; 10(1):3511.
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Gonz?lez MI, Kazanietz MG, Robinson MB. Regulation of the neuronal glutamate transporter excitatory amino acid carrier-1 (EAAC1) by different protein kinase C subtypes. Mol Pharmacol. 2002 Oct; 62(4):901-10.
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Gonzalez R, Ebbinghaus S, Henthorn TK, Miller D, Kraft AS. Treatment of patients with metastatic melanoma with bryostatin-1--a phase II study. Melanoma Res. 1999 Dec; 9(6):599-606.