 Pentobarbital
"Pentobarbital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
| Descriptor ID |
D010424
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| MeSH Number(s) |
D03.383.742.698.253.593
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pentobarbital".
Below are MeSH descriptors whose meaning is more specific than "Pentobarbital".
This graph shows the total number of publications written about "Pentobarbital" by people in this website by year, and whether "Pentobarbital" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pentobarbital" by people in Profiles.
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Bodor GS, Rands AJ. Quantitative LC-MS/MS Method for the Simultaneous Measurement of Six Antiepileptics and Pentobarbital in Human Serum. Methods Mol Biol. 2024; 2737:43-54.
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Houk AK, Harmon LA. Abdominal Compartment Syndrome: A Rare Complication of Pentobarbital Treatment for New-Onset Refractory Status Epilepticus. Am Surg. 2020 Mar 01; 86(3):e150-e152.
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Larson ED, Vandenbeuch A, Voigt A, Meyerhof W, Kinnamon SC, Finger TE. The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. J Neurosci. 2015 Dec 02; 35(48):15984-95.
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Mellion SA, Bennett KS, Ellsworth GL, Moore K, Riva-Cambrin J, Metzger RR, Bratton SL. High-dose barbiturates for refractory intracranial hypertension in children with severe traumatic brain injury. Pediatr Crit Care Med. 2013 Mar; 14(3):239-47.
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Kowalski RG, Ziai WC, Rees RN, Werner JK, Kim G, Goodwin H, Geocadin RG. Third-line antiepileptic therapy and outcome in status epilepticus: the impact of vasopressor use and prolonged mechanical ventilation. Crit Care Med. 2012 Sep; 40(9):2677-84.
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Barberio M, Reiter PD, Kaufman J, Knupp K, Dobyns EL. Continuous infusion pentobarbital for refractory status epilepticus in children. J Child Neurol. 2012 Jun; 27(6):721-6.
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Joksovic PM, Brimelow BC, Murbarti?n J, Perez-Reyes E, Todorovic SM. Contrasting anesthetic sensitivities of T-type Ca2+ channels of reticular thalamic neurons and recombinant Ca(v)3.3 channels. Br J Pharmacol. 2005 Jan; 144(1):59-70.
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Lieggi CC, Artwohl JE, Leszczynski JK, Rodriguez NA, Fickbohm BL, Fortman JD. Efficacy and safety of stored and newly prepared tribromoethanol in ICR mice. Contemp Top Lab Anim Sci. 2005 Jan; 44(1):17-22.
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Claassen J, Mayer SA, Kowalski RG, Emerson RG, Hirsch LJ. Detection of electrographic seizures with continuous EEG monitoring in critically ill patients. Neurology. 2004 May 25; 62(10):1743-8.
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Petroff BK, Croutch CR, Hunter DM, Wierman ME, Gao X. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) stimulates gonadotropin secretion in the immature female Sprague-Dawley rat through a pentobarbital- and estradiol-sensitive mechanism but does not alter gonadotropin-releasing hormone (GnRH) secretion by immortalized GnRH neurons in vitro. Biol Reprod. 2003 Jun; 68(6):2100-6.
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