Propylthiouracil
"Propylthiouracil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Descriptor ID |
D011441
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MeSH Number(s) |
D03.383.742.698.875.842.708
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Propylthiouracil".
Below are MeSH descriptors whose meaning is more specific than "Propylthiouracil".
This graph shows the total number of publications written about "Propylthiouracil" by people in this website by year, and whether "Propylthiouracil" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 1 | 0 | 1 | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Propylthiouracil" by people in Profiles.
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Martin LE, Kay KE, Torregrossa AM. Rats are unable to discriminate quinine from diverse bitter stimuli. Am J Physiol Regul Integr Comp Physiol. 2019 12 01; 317(6):R793-R802.
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Kim HJ, Kim BH, Han YS, Yang I, Kim KJ, Dong SH, Kim HJ, Chang YW, Lee JI, Chang R. The incidence and clinical characteristics of symptomatic propylthiouracil-induced hepatic injury in patients with hyperthyroidism: a single-center retrospective study. Am J Gastroenterol. 2001 Jan; 96(1):165-9.
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Samuels MH, Wierman ME, Wang C, Ridgway EC. The effect of altered thyroid status on pituitary hormone messenger ribonucleic acid concentrations in the rat. Endocrinology. 1989 May; 124(5):2277-82.
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Burstein PJ, Draznin B, Johnson CJ, Schalch DS. The effect of hypothyroidism on growth, serum growth hormone, the growth hormone-dependent somatomedin, insulin-like growth factor, and its carrier protein in rats. Endocrinology. 1979 Apr; 104(4):1107-11.
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