Blast Crisis
"Blast Crisis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An advanced phase of chronic myelogenous leukemia, characterized by a rapid increase in the proportion of immature white blood cells (blasts) in the blood and bone marrow to greater than 30%.
Descriptor ID |
D001752
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MeSH Number(s) |
C04.557.337.539.250.100 C04.697.098.500.110 C15.378.190.636.370.100 C23.550.727.098.500.110
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Concept/Terms |
Blast Crisis- Blast Crisis
- Blast Crises
- Crises, Blast
- Crisis, Blast
- Blast Phase
- Blast Phases
- Phase, Blast
- Phases, Blast
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Below are MeSH descriptors whose meaning is more general than "Blast Crisis".
- Diseases [C]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Leukemia [C04.557.337]
- Leukemia, Myeloid [C04.557.337.539]
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive [C04.557.337.539.250]
- Blast Crisis [C04.557.337.539.250.100]
- Neoplastic Processes [C04.697]
- Carcinogenesis [C04.697.098]
- Cell Transformation, Neoplastic [C04.697.098.500]
- Blast Crisis [C04.697.098.500.110]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Bone Marrow Diseases [C15.378.190]
- Myeloproliferative Disorders [C15.378.190.636]
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive [C15.378.190.636.370]
- Blast Crisis [C15.378.190.636.370.100]
- Pathological Conditions, Signs and Symptoms [C23]
- Pathologic Processes [C23.550]
- Neoplastic Processes [C23.550.727]
- Carcinogenesis [C23.550.727.098]
- Cell Transformation, Neoplastic [C23.550.727.098.500]
- Blast Crisis [C23.550.727.098.500.110]
Below are MeSH descriptors whose meaning is more specific than "Blast Crisis".
This graph shows the total number of publications written about "Blast Crisis" by people in this website by year, and whether "Blast Crisis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 2003 | 1 | 0 | 1 | 2005 | 0 | 1 | 1 | 2007 | 1 | 1 | 2 | 2010 | 0 | 2 | 2 | 2011 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2016 | 1 | 1 | 2 | 2017 | 1 | 0 | 1 | 2018 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Blast Crisis" by people in Profiles.
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Liu APY, Kelsey MM, Sabbaghian N, Park SH, Deal CL, Esbenshade AJ, Ploner O, Peet A, Traunecker H, Ahmed YHE, Zacharin M, Tiulpakov A, Lapshina AM, Walter AW, Dutta P, Rai A, Korbonits M, de Kock L, Nichols KE, Foulkes WD, Priest JR. Clinical Outcomes and Complications of Pituitary Blastoma. J Clin Endocrinol Metab. 2021 01 23; 106(2):351-363.
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Spagnuolo M, Regazzo G, De Dominici M, Sacconi A, Pelosi A, Korita E, Marchesi F, Pisani F, Magenta A, Lulli V, Cordone I, Mengarelli A, Strano S, Blandino G, Rizzo MG, Calabretta B. Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells. Haematologica. 2019 01; 104(1):82-92.
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Dourado KMC, Baik J, Oliveira VKP, Beltrame M, Yamamoto A, Theuer CP, Figueiredo CAV, Verneris MR, Perlingeiro RCR. Endoglin: a novel target for therapeutic intervention in acute leukemias revealed in xenograft mouse models. Blood. 2017 05 04; 129(18):2526-2536.
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Kolenova A, Maloney KW, Hunger SP. Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia or Chronic Myeloid Leukemia in Lymphoid Blast Crisis. J Pediatr Hematol Oncol. 2016 08; 38(6):e193-5.
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Ye H, Adane B, Khan N, Sullivan T, Minhajuddin M, Gasparetto M, Stevens B, Pei S, Balys M, Ashton JM, Klemm DJ, Woolthuis CM, Stranahan AW, Park CY, Jordan CT. Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche. Cell Stem Cell. 2016 07 07; 19(1):23-37.
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Ashton JM, Balys M, Neering SJ, Hassane DC, Cowley G, Root DE, Miller PG, Ebert BL, McMurray HR, Land H, Jordan CT. Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells. Cell Stem Cell. 2012 Sep 07; 11(3):359-72.
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Huang M, Whang P, Chodaparambil JV, Pollyea DA, Kusler B, Xu L, Felsher DW, Mitchell BS. Reactive oxygen species regulate nucleostemin oligomerization and protein degradation. J Biol Chem. 2011 Apr 01; 286(13):11035-46.
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Ito T, Kwon HY, Zimdahl B, Congdon KL, Blum J, Lento WE, Zhao C, Lagoo A, Gerrard G, Foroni L, Goldman J, Goh H, Kim SH, Kim DW, Chuah C, Oehler VG, Radich JP, Jordan CT, Reya T. Regulation of myeloid leukaemia by the cell-fate determinant Musashi. Nature. 2010 Aug 05; 466(7307):765-8.
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Godal R, Bachanova V, Gleason M, McCullar V, Yun GH, Cooley S, Verneris MR, McGlave PB, Miller JS. Natural killer cell killing of acute myelogenous leukemia and acute lymphoblastic leukemia blasts by killer cell immunoglobulin-like receptor-negative natural killer cells after NKG2A and LIR-1 blockade. Biol Blood Marrow Transplant. 2010 May; 16(5):612-21.
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Stuart SA, Minami Y, Wang JY. The CML stem cell: evolution of the progenitor. Cell Cycle. 2009 May 01; 8(9):1338-43.
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