 Genes, abl
"Genes, abl" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.
| Descriptor ID |
D016313
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| MeSH Number(s) |
G05.360.340.024.340.375.500.791.100
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| Concept/Terms |
bcr-v-abl Oncogenes- bcr-v-abl Oncogenes
- Oncogene, bcr-v-abl
- Oncogenes, bcr-v-abl
- bcr v abl Oncogenes
- bcr-v-abl Oncogene
abl Oncogene- abl Oncogene
- Oncogene, abl
- Oncogenes, abl
- abl Oncogenes
- v-abl Oncogenes
- Oncogene, v-abl
- Oncogenes, v-abl
- v abl Oncogenes
- v-abl Oncogene
- v-abl Genes
- Gene, v-abl
- Genes, v-abl
- v abl Genes
- v-abl Gene
bcr-abl Proto-Oncogenes- bcr-abl Proto-Oncogenes
- Proto-Oncogene, bcr-abl
- Proto-Oncogenes, bcr-abl
- bcr abl Proto Oncogenes
- bcr-abl Proto-Oncogene
c-abl Genes- c-abl Genes
- Gene, c-abl
- Genes, c-abl
- c abl Genes
- c-abl Gene
- c-abl Proto-Oncogenes
- Proto-Oncogene, c-abl
- Proto-Oncogenes, c-abl
- c abl Proto Oncogenes
- c-abl Proto-Oncogene
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Below are MeSH descriptors whose meaning is more general than "Genes, abl".
Below are MeSH descriptors whose meaning is more specific than "Genes, abl".
This graph shows the total number of publications written about "Genes, abl" by people in this website by year, and whether "Genes, abl" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, abl" by people in Profiles.
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Young FM, Campbell A, Emo KL, Jansson J, Wang PY, Jordan CT, Mullen CA. High-risk acute lymphoblastic leukemia cells with bcr-abl and INK4A/ARF mutations retain susceptibility to alloreactive T cells. Biol Blood Marrow Transplant. 2008 Jun; 14(6):622-30.
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Duncan EA, Goetz CA, Stein SJ, Mayo KJ, Skaggs BJ, Ziegelbauer K, Sawyers CL, Baldwin AS. IkappaB kinase beta inhibition induces cell death in Imatinib-resistant and T315I Dasatinib-resistant BCR-ABL+ cells. Mol Cancer Ther. 2008 Feb; 7(2):391-7.
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Chau BN, Chen TT, Wan YY, DeGregori J, Wang JY. Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation. Mol Cell Biol. 2004 May; 24(10):4438-47.
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Heyeck SD, Berg LJ. Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk. Proc Natl Acad Sci U S A. 1993 Jan 15; 90(2):669-73.
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