 Clustered Regularly Interspaced Short Palindromic Repeats
"Clustered Regularly Interspaced Short Palindromic Repeats" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive antiviral defense systems.
| Descriptor ID |
D064112
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| MeSH Number(s) |
G02.111.570.080.708.800.325.500 G05.360.080.708.800.325.500 G05.360.340.024.850.069
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| Concept/Terms |
Clustered Regularly Interspaced Short Palindromic Repeats- Clustered Regularly Interspaced Short Palindromic Repeats
- CRISPRs
- CRISPR
- CRISPR Sequences
- CRISPR Sequence
- Sequence, CRISPR
- Sequences, CRISPR
- Clustered Regularly Interspaced Short Palindromic Repeat
- CRISPR Elements
- CRISPR Element
- Element, CRISPR
- Elements, CRISPR
CRISPR Spacers- CRISPR Spacers
- CRISPR Spacer
- Spacer, CRISPR
- Spacers, CRISPR
- CRISPR Spacer Sequences
- CRISPR Spacer Sequence
- Sequence, CRISPR Spacer
- Sequences, CRISPR Spacer
- Spacer Sequence, CRISPR
- Spacer Sequences, CRISPR
CRISPR-Cas Loci- CRISPR-Cas Loci
- CRISPR Cas Loci
- CRISPR-Cas Locus
- Loci, CRISPR-Cas
- Locus, CRISPR-Cas
CRISPR Loci- CRISPR Loci
- Loci, CRISPR
- Locus, CRISPR
- CRISPR Clusters
- CRISPR Cluster
- Cluster, CRISPR
- Clusters, CRISPR
- CRISPR Locus
- CRISPR Arrays
- Array, CRISPR
- Arrays, CRISPR
- CRISPR Array
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Below are MeSH descriptors whose meaning is more general than "Clustered Regularly Interspaced Short Palindromic Repeats".
Below are MeSH descriptors whose meaning is more specific than "Clustered Regularly Interspaced Short Palindromic Repeats".
This graph shows the total number of publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in this website by year, and whether "Clustered Regularly Interspaced Short Palindromic Repeats" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 2 | 3 | | 2017 | 2 | 1 | 3 | | 2018 | 1 | 3 | 4 | | 2019 | 1 | 1 | 2 | | 2020 | 0 | 3 | 3 | | 2021 | 0 | 3 | 3 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in Profiles.
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Pividori M, Lu S, Li B, Su C, Johnson ME, Wei WQ, Feng Q, Namjou B, Kiryluk K, Kullo IJ, Luo Y, Sullivan BD, Voight BF, Skarke C, Ritchie MD, Grant SFA, Greene CS. Projecting genetic associations through gene expression patterns highlights disease etiology and drug mechanisms. Nat Commun. 2023 09 09; 14(1):5562.
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Bek JW, Shochat C, De Clercq A, De Saffel H, Boel A, Metz J, Rodenburg F, Karasik D, Willaert A, Coucke PJ. Lrp5 Mutant and Crispant Zebrafish Faithfully Model Human Osteoporosis, Establishing the Zebrafish as a Platform for CRISPR-Based Functional Screening of Osteoporosis Candidate Genes. J Bone Miner Res. 2021 09; 36(9):1749-1764.
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Wang T, Pine AR, Kotini AG, Yuan H, Zamparo L, Starczynowski DT, Leslie C, Papapetrou EP. Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets. Cell Stem Cell. 2021 06 03; 28(6):1074-1089.e7.
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Wang E, Zhou H, Nadorp B, Cayanan G, Chen X, Yeaton AH, Nomikou S, Witkowski MT, Narang S, Kloetgen A, Thandapani P, Ravn-Boess N, Tsirigos A, Aifantis I. Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation. Cell Stem Cell. 2021 04 01; 28(4):718-731.e6.
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Long Y, Cech TR. Targeted mutagenesis in human iPSCs using CRISPR genome-editing tools. Methods. 2021 07; 191:44-58.
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Fenster JA, Eckert CA. High-Throughput Functional Genomics for Energy Production. Curr Opin Biotechnol. 2021 02; 67:7-14.
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Liu R, Liang L, Freed EF, Choudhury A, Eckert CA, Gill RT. Engineering regulatory networks for complex phenotypes in E. coli. Nat Commun. 2020 08 13; 11(1):4050.
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Kitagawa A, Kizub I, Jacob C, Michael K, D'Alessandro A, Reisz JA, Grzybowski M, Geurts AM, Rocic P, Gupte R, Miano JM, Gupte SA. CRISPR-Mediated Single Nucleotide Polymorphism Modeling in Rats Reveals Insight Into Reduced Cardiovascular Risk Associated With Mediterranean G6PD Variant. Hypertension. 2020 08; 76(2):523-532.
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Esbin MN, Whitney ON, Chong S, Maurer A, Darzacq X, Tjian R. Overcoming the bottleneck to widespread testing: a rapid review of nucleic acid testing approaches for COVID-19 detection. RNA. 2020 07; 26(7):771-783.
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Iwasaki RS, Ozdilek BA, Garst AD, Choudhury A, Batey RT. Small molecule regulated sgRNAs enable control of genome editing in E. coli by Cas9. Nat Commun. 2020 Mar 13; 11(1):1394.
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