 Depressive Disorder, Treatment-Resistant
"Depressive Disorder, Treatment-Resistant" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant therapies. (Campbell's Psychiatric Dictionary, 9th ed.)
| Descriptor ID |
D061218
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| MeSH Number(s) |
F03.600.300.388
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| Concept/Terms |
Depressive Disorder, Treatment-Resistant- Depressive Disorder, Treatment-Resistant
- Depressive Disorder, Treatment Resistant
- Depressive Disorders, Treatment-Resistant
- Disorder, Treatment-Resistant Depressive
- Disorders, Treatment-Resistant Depressive
- Treatment-Resistant Depressive Disorder
- Treatment-Resistant Depressive Disorders
- Refractory Depression
- Depression, Refractory
- Depressions, Refractory
- Refractory Depressions
- Therapy-Resistant Depression
- Depression, Therapy-Resistant
- Depressions, Therapy-Resistant
- Therapy Resistant Depression
- Therapy-Resistant Depressions
- Treatment Resistant Depression
- Depression, Treatment Resistant
- Depressions, Treatment Resistant
- Resistant Depression, Treatment
- Resistant Depressions, Treatment
- Treatment Resistant Depressions
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Below are MeSH descriptors whose meaning is more general than "Depressive Disorder, Treatment-Resistant".
Below are MeSH descriptors whose meaning is more specific than "Depressive Disorder, Treatment-Resistant".
This graph shows the total number of publications written about "Depressive Disorder, Treatment-Resistant" by people in this website by year, and whether "Depressive Disorder, Treatment-Resistant" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Depressive Disorder, Treatment-Resistant" by people in Profiles.
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Himes LM, Mayberg HS, Husain MM, Holtzheimer PE, Lozano AM, Kennedy SH, Gross RE, Kopell BH, Figee M, Slavin KV, Pilitsis JG, Neimat JS, Hamani C, Pouratian N, Giacobbe P, Mogilner AY, Nanduri D, Cheeran BJ, Pathak YJ, Riva-Posse P. Revisiting subcallosal cingulate deep brain stimulation for depression: Long-term safety and effectiveness outcomes from a pooled analysis of 172 implanted patients. Brain Stimul. 2025 Sep-Oct; 18(5):1632-1640.
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Niciu MJ, Meisner RC, Carr BR, Farooqui AA, Feifel D, Kaplin A, Kendrick EJ, Kim PM, Schneck CD, Vande Voort JL, Parikh SV. National Network of Depression Centers position statement: Insurance coverage for intravenous ketamine in treatment-resistant major depressive disorder. J Affect Disord. 2024 02 01; 346:221-222.
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Wulff AB, Nichols CD, Thompson SM. Preclinical perspectives on the mechanisms underlying the therapeutic actions of psilocybin in psychiatric disorders. Neuropharmacology. 2023 06 15; 231:109504.
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Gogulski J, Ross JM, Talbot A, Cline CC, Donati FL, Munot S, Kim N, Gibbs C, Bastin N, Yang J, Minasi C, Sarkar M, Truong J, Keller CJ. Personalized Repetitive Transcranial Magnetic Stimulation for Depression. Biol Psychiatry Cogn Neurosci Neuroimaging. 2023 04; 8(4):351-360.
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Sendi MSE, Waters AC, Tiruvadi V, Riva-Posse P, Crowell A, Isbaine F, Gale JT, Choi KS, Gross RE, S Mayberg H, Mahmoudi B. Intraoperative neural signals predict rapid antidepressant effects of deep brain stimulation. Transl Psychiatry. 2021 11 03; 11(1):551.
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Zisook S, Johnson GR, Hicks P, Chen P, Beresford T, Michalets JP, Rao S, Thase ME, Wilcox J, Sevilimedu V, Mohamed S. Continuation phase treatment outcomes for switching, combining, or augmenting strategies for treatment-resistant major depressive disorder: A VAST-D report. Depress Anxiety. 2021 02; 38(2):185-195.
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Crowell AL, Riva-Posse P, Holtzheimer PE, Garlow SJ, Kelley ME, Gross RE, Denison L, Quinn S, Mayberg HS. Long-Term Outcomes of Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Depression. Am J Psychiatry. 2019 11 01; 176(11):949-956.
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Riva-Posse P, Inman CS, Choi KS, Crowell AL, Gross RE, Hamann S, Mayberg HS. Autonomic arousal elicited by subcallosal cingulate stimulation is explained by white matter connectivity. Brain Stimul. 2019 May - Jun; 12(3):743-751.
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Cullen KR, Amatya P, Roback MG, Albott CS, Westlund Schreiner M, Ren Y, Eberly LE, Carstedt P, Samikoglu A, Gunlicks-Stoessel M, Reigstad K, Horek N, Tye S, Lim KO, Klimes-Dougan B. Intravenous Ketamine for Adolescents with Treatment-Resistant Depression: An Open-Label Study. J Child Adolesc Psychopharmacol. 2018 09; 28(7):437-444.
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Holtzheimer PE, Husain MM, Lisanby SH, Taylor SF, Whitworth LA, McClintock S, Slavin KV, Berman J, McKhann GM, Patil PG, Rittberg BR, Abosch A, Pandurangi AK, Holloway KL, Lam RW, Honey CR, Neimat JS, Henderson JM, DeBattista C, Rothschild AJ, Pilitsis JG, Espinoza RT, Petrides G, Mogilner AY, Matthews K, Peichel D, Gross RE, Hamani C, Lozano AM, Mayberg HS. Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multisite, randomised, sham-controlled trial. Lancet Psychiatry. 2017 11; 4(11):839-849.
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