 Depressive Disorder, Major
"Depressive Disorder, Major" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.
| Descriptor ID |
D003865
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| MeSH Number(s) |
F03.600.300.375
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| Concept/Terms |
Depressive Disorder, Major- Depressive Disorder, Major
- Depressive Disorders, Major
- Disorder, Major Depressive
- Disorders, Major Depressive
- Major Depressive Disorders
- Major Depressive Disorder
Paraphrenia, Involutional- Paraphrenia, Involutional
- Involutional Paraphrenia
- Involutional Paraphrenias
- Paraphrenias, Involutional
Depression, Involutional- Depression, Involutional
- Involutional Depression
- Melancholia, Involutional
- Involutional Melancholia
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Below are MeSH descriptors whose meaning is more general than "Depressive Disorder, Major".
Below are MeSH descriptors whose meaning is more specific than "Depressive Disorder, Major".
This graph shows the total number of publications written about "Depressive Disorder, Major" by people in this website by year, and whether "Depressive Disorder, Major" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 | | 1999 | 4 | 0 | 4 | | 2000 | 2 | 0 | 2 | | 2001 | 1 | 1 | 2 | | 2002 | 2 | 0 | 2 | | 2003 | 2 | 1 | 3 | | 2004 | 4 | 2 | 6 | | 2005 | 11 | 0 | 11 | | 2006 | 8 | 1 | 9 | | 2007 | 6 | 3 | 9 | | 2008 | 8 | 3 | 11 | | 2009 | 7 | 0 | 7 | | 2010 | 8 | 2 | 10 | | 2011 | 11 | 5 | 16 | | 2012 | 12 | 2 | 14 | | 2013 | 14 | 5 | 19 | | 2014 | 12 | 3 | 15 | | 2015 | 9 | 2 | 11 | | 2016 | 20 | 1 | 21 | | 2017 | 13 | 2 | 15 | | 2018 | 10 | 1 | 11 | | 2019 | 14 | 1 | 15 | | 2020 | 6 | 2 | 8 | | 2021 | 11 | 1 | 12 | | 2022 | 10 | 0 | 10 | | 2023 | 14 | 1 | 15 | | 2024 | 11 | 2 | 13 | | 2025 | 3 | 0 | 3 |
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Below are the most recent publications written about "Depressive Disorder, Major" by people in Profiles.
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Shoaibi A, Ostropolets A, Weaver J, Rao GA, Golozar A, Swerdel J, Huser V, Adam A, Alshammari T, Anikpezie N, Baumgartner WA, Brand M, Fan R, Kanter AS, Kern D, Melisa S, Minty E, Mo J, Oluwalade B, Schilling LM, Spence H, Stocking JC, Zhang L, Ryan P. Variation in Phenotype Definitions in Observational Clinical Research: A Review of Three Conditions. AMIA Annu Symp Proc. 2024; 2024:1021-1029.
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Ozmen O, Rush E, Park BH, Jones M, Trafton J, Brenner L, Rupper RW, Ward M, Nebeker JR, Pizer SD. Combining Machine Learning and Comparative Effectiveness Methodology to Study Primary Care Pharmacotherapy Pathways for Veterans With Depression. Med Care. 2025 Jun 01; 63(6):422-429.
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Kang SJ, Guo W, Zipunnikov V, Glaus J, Lamers F, Strippoli MF, Marques-Vidal P, Vaucher J, de La Harpe R, Vollenweider P, Preisig M, Merikangas KR, Leroux A. Impact of cardiovascular risk factors on associations between state and trait indices of major depression disorder and objectively assessed physical activity, sleep and circadian rhythmicity within a population based cohort. J Affect Disord. 2025 Jun 01; 378:360-372.
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Kypriotakis G, Cinciripini PM, Green CE, Lawrence D, Anthenelli RM, Minnix JA, Beneventi D, Morris C, Karam-Hage M, Blalock JA. Effects of Varenicline, Bupropion, Nicotine Patch, and Placebo on Treating Smoking Among Persons With Current or Past Major Depressive Disorder: Secondary Analysis of a Double-Blind, Randomized, Placebo-Controlled Trial. Am J Psychiatry. 2025 Feb 01; 182(2):174-186.
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Morey RA, Zheng Y, Bayly H, Sun D, Garrett ME, Gasperi M, Maihofer AX, Baird CL, Grasby KL, Huggins AA, Haswell CC, Thompson PM, Medland S, Gustavson DE, Panizzon MS, Kremen WS, Nievergelt CM, Ashley-Koch AE, Logue MW. Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture. Transl Psychiatry. 2024 Oct 24; 14(1):451.
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Adams MJ, Thorp JG, Jermy BS, Kwong ASF, K?iv K, Grotzinger AD, Nivard MG, Marshall S, Milaneschi Y, Baune BT, M?ller-Myhsok B, Penninx BWJH, Boomsma DI, Levinson DF, Breen G, Pistis G, Grabe HJ, Tiemeier H, Berger K, Rietschel M, Magnusson PK, Uher R, Hamilton SP, Lucae S, Lehto K, Li QS, Byrne EM, Hickie IB, Martin NG, Medland SE, Wray NR, Tucker-Drob EM, Lewis CM, McIntosh AM, Derks EM. Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts. Psychol Med. 2024 Sep; 54(12):3459-3468.
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Goldstein KE, Pietrzak RH, Challman KN, Chu KW, Beck KD, Brenner LA, Interian A, Myers CE, Shafritz KM, Szeszko PR, Goodman M, Haznedar MM, Hazlett EA. Multi-modal risk factors differentiate suicide attempters from ideators in military veterans with major depressive disorder. J Affect Disord. 2025 Jan 15; 369:588-598.
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Kang SJ, Leroux A, Guo W, Dey D, Strippoli MF, Di J, Vaucher J, Marques-Vidal P, Vollenweider P, Preisig M, Merikangas KR, Zipunnikov V. Integrative Modeling of Accelerometry-Derived Sleep, Physical Activity, and Circadian Rhythm Domains With Current or Remitted Major Depression. JAMA Psychiatry. 2024 Sep 01; 81(9):911-918.
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Qiu L, Liang C, Kochunov P, Hutchison KE, Sui J, Jiang R, Zhi D, Vergara VM, Yang X, Zhang D, Fu Z, Bustillo JR, Qi S, Calhoun VD. Associations of alcohol and tobacco use with psychotic, depressive and developmental disorders revealed via multimodal neuroimaging. Transl Psychiatry. 2024 Aug 07; 14(1):326.
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Page CE, Epperson CN, Novick AM, Duffy KA, Thompson SM. Beyond the serotonin deficit hypothesis: communicating a neuroplasticity framework of major depressive disorder. Mol Psychiatry. 2024 Dec; 29(12):3802-3813.
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