Trefoil Factor-2
"Trefoil Factor-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 106 amino acid (12 kDa) trefoil factor that contains two trefoil domains and associates with MUCIN-6. It is expressed in the GASTROINTESTINAL TRACT by cells of BRUNNER GLANDS; PYLORIC GLANDS and mucous neck cells. It inhibits GASTROINTESTINAL MOTILITY and GASTRIC ACID secretion and may help maintain the structural integrity of gastric mucus.
| Descriptor ID |
D000071164
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| MeSH Number(s) |
D12.644.937.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trefoil Factor-2".
Below are MeSH descriptors whose meaning is more specific than "Trefoil Factor-2".
This graph shows the total number of publications written about "Trefoil Factor-2" by people in this website by year, and whether "Trefoil Factor-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trefoil Factor-2" by people in Profiles.
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Louis NA, Hamilton KE, Canny G, Shekels LL, Ho SB, Colgan SP. Selective induction of mucin-3 by hypoxia in intestinal epithelia. J Cell Biochem. 2006 Dec 15; 99(6):1616-27.
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Furuta GT, Turner JR, Taylor CT, Hershberg RM, Comerford K, Narravula S, Podolsky DK, Colgan SP. Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia. J Exp Med. 2001 May 07; 193(9):1027-34.