 Orotate Phosphoribosyltransferase
"Orotate Phosphoribosyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. EC 2.4.2.10.
| Descriptor ID |
D009962
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| MeSH Number(s) |
D08.811.913.400.725.700
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| Concept/Terms |
Orotate Phosphoribosyltransferase- Orotate Phosphoribosyltransferase
- Phosphoribosyltransferase, Orotate
- Orotidylic Acid Phosphorylase
- Phosphorylase, Orotidylic Acid
- Orotidine-5'-Phosphate Pyrophosphorylase
- Orotidine 5' Phosphate Pyrophosphorylase
- Pyrophosphorylase, Orotidine-5'-Phosphate
- OMPase
- Orotidine-5'-Monophosphate Phosphohydrolase
- Orotidine 5' Monophosphate Phosphohydrolase
- Phosphohydrolase, Orotidine-5'-Monophosphate
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Below are MeSH descriptors whose meaning is more general than "Orotate Phosphoribosyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Orotate Phosphoribosyltransferase".
This graph shows the total number of publications written about "Orotate Phosphoribosyltransferase" by people in this website by year, and whether "Orotate Phosphoribosyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Orotate Phosphoribosyltransferase" by people in Profiles.
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Wortmann SB, Chen MA, Colombo R, Pontoglio A, Alhaddad B, Botto LD, Yuzyuk T, Coughlin CR, Descartes M, Grunewald S, Maranda B, Mills PB, Pitt J, Potente C, Rodenburg R, Kluijtmans LA, Sampath S, Pai EF, Wevers RA, Tiller GE. Mild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences. J Inherit Metab Dis. 2017 05; 40(3):423-431.
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Garc?a-Bayona L, Garavito MF, Lozano GL, Vasquez JJ, Myers K, Fry WE, Bernal A, Zimmermann BH, Restrepo S. De novo pyrimidine biosynthesis in the oomycete plant pathogen Phytophthora infestans. Gene. 2014 Mar 10; 537(2):312-21.
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Griffith M, Mwenifumbo JC, Cheung PY, Paul JE, Pugh TJ, Tang MJ, Chittaranjan S, Morin RD, Asano JK, Ally AA, Miao L, Lee A, Chan SY, Taylor G, Severson T, Hou YC, Griffith OL, Cheng GS, Novik K, Moore R, Luk M, Owen D, Brown CJ, Morin GB, Gill S, Tai IT, Marra MA. Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer. Pharmacogenomics J. 2013 Apr; 13(2):148-58.
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Bai X, Larsen M, Meinhardt F. The URA5 gene encoding orotate-phosphoribosyl transferase of the yeast Kluyveromyces lactis: cloning, sequencing and use as a selectable marker. Yeast. 1999 Sep 30; 15(13):1393-8.
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