| 
																	
																		 
																		 Porphyrins
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Porphyrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.
    
			 
				
				
					
						| Descriptor ID | D011166 |  
						| MeSH Number(s) | D03.383.129.578.840.500 D03.633.400.909.500 D04.345.783.500 D23.767.727 |  
						| Concept/Terms |  |  
				Below are MeSH descriptors whose meaning is more general than "Porphyrins". 
				Below are MeSH descriptors whose meaning is more specific than "Porphyrins". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Porphyrins" by people in this website by year, and whether "Porphyrins" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1996 | 1 | 0 | 1 |  | 2002 | 1 | 0 | 1 |  | 2006 | 1 | 0 | 1 |  | 2007 | 1 | 0 | 1 |  | 2008 | 1 | 0 | 1 |  | 2009 | 1 | 0 | 1 |  | 2010 | 0 | 1 | 1 |  | 2011 | 1 | 0 | 1 |  | 2013 | 1 | 0 | 1 |  | 2014 | 0 | 1 | 1 |  | 2015 | 3 | 1 | 4 |  | 2017 | 0 | 1 | 1 |  | 2020 | 0 | 2 | 2 |  | 2023 | 1 | 0 | 1 |  | 2024 | 0 | 1 | 1 | 
 
                    To return to the timeline, click here. 
				Below are the most recent publications written about "Porphyrins" by people in Profiles. 		
					
								
								Johnson K, Seidel JM, Cech TR. Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. RNA. 2024 08 16; 30(9):1213-1226.
								Witthauer L, Roussakis E, Cascales JP, Goss A, Li X, Cralley A, Yoeli D, Moore HB, Wang Z, Wang Y, Li B, Huang CA, Moore EE, Evans CL. Development and in-vivo validation of a portable phosphorescence lifetime-based fiber-optic oxygen sensor. Sci Rep. 2023 09 07; 13(1):14782.
								Loth MK, Guariglia SR, Re DB, Perez J, de Paiva VN, Dziedzic JL, Chambers JW, Azzam DJ, Guilarte TR. A Novel Interaction of Translocator Protein 18?kDa (TSPO) with NADPH Oxidase in Microglia. Mol Neurobiol. 2020 Nov; 57(11):4467-4487.
								Jewell MP, Saccomano SC, David AA, Harris JK, Zemanick ET, Cash KJ. Nanodiagnostics to monitor biofilm oxygen metabolism for antibiotic susceptibility testing. Analyst. 2020 Jun 07; 145(11):3996-4003.
								Muhanna N, Chan HHL, Townson JL, Jin CS, Ding L, Valic MS, Douglas CM, MacLaughlin CM, Chen J, Zheng G, Irish JC. Photodynamic therapy enables tumor-specific ablation in preclinical models of thyroid cancer. Endocr Relat Cancer. 2020 02; 27(2):41-53.
								Gaurav R, Varasteh JT, Weaver MR, Jacobson SR, Hernandez-Lagunas L, Liu Q, Nozik-Grayck E, Chu HW, Alam R, Nordestgaard BG, Kobylecki CJ, Afzal S, Chupp GL, Bowler RP. The R213G polymorphism in SOD3 protects against allergic airway inflammation. JCI Insight. 2017 09 07; 2(17).
								Muhanna N, Jin CS, Huynh E, Chan H, Qiu Y, Jiang W, Cui L, Burgess L, Akens MK, Chen J, Irish JC, Zheng G. Phototheranostic Porphyrin Nanoparticles Enable Visualization and Targeted Treatment of Head and Neck Cancer in Clinically Relevant Models. Theranostics. 2015; 5(12):1428-43.
								Muhanna N, Cui L, Chan H, Burgess L, Jin CS, MacDonald TD, Huynh E, Wang F, Chen J, Irish JC, Zheng G. Multimodal Image-Guided Surgical and Photodynamic Interventions in Head and Neck Cancer: From Primary Tumor to Metastatic Drainage. Clin Cancer Res. 2016 Feb 15; 22(4):961-70.
								Patriquin L, Merrick DT, Hill D, Holcomb RG, Lemieux ME, Bennett G, Karia B, Rebel VI, Bauer T. Early Detection of Lung Cancer with Meso Tetra (4-Carboxyphenyl) Porphyrin-Labeled Sputum. J Thorac Oncol. 2015 Sep; 10(9):1311-1318.
								Cui L, Lin Q, Jin CS, Jiang W, Huang H, Ding L, Muhanna N, Irish JC, Wang F, Chen J, Zheng G. A PEGylation-Free Biomimetic Porphyrin Nanoplatform for Personalized Cancer Theranostics. ACS Nano. 2015; 9(4):4484-95. | 
																	
																		
																			
																					People  People who have written about this concept._ 
    
        Similar Concepts   
        People who have written about this concept.
     _ 
    
        Top Journals   
        Top journals in which articles about this concept have been published.
     |