 Sodium Nitrite
"Sodium Nitrite" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nitrous acid sodium salt. Used in many industrial processes, in meat curing, coloring, and preserving, and as a reagent in ANALYTICAL CHEMISTRY TECHNIQUES. It is used therapeutically as an antidote in cyanide poisoning. The compound is toxic and mutagenic and will react in vivo with secondary or tertiary amines thereby producing highly carcinogenic nitrosamines.
| Descriptor ID |
D012977
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| MeSH Number(s) |
D01.625.600.600.800 D01.857.775
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sodium Nitrite".
Below are MeSH descriptors whose meaning is more specific than "Sodium Nitrite".
This graph shows the total number of publications written about "Sodium Nitrite" by people in this website by year, and whether "Sodium Nitrite" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 2 | 1 | 3 | | 2015 | 3 | 0 | 3 | | 2016 | 1 | 0 | 1 | | 2020 | 2 | 0 | 2 | | 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Sodium Nitrite" by people in Profiles.
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Mudan A, Lebin JA, Smollin CG. Comment on "Rising incidence and high mortality in intentional sodium nitrite exposures reported to US poison centers". Clin Toxicol (Phila). 2022 01; 60(1):140.
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Rossman MJ, Gioscia-Ryan RA, Santos-Parker JR, Ziemba BP, Lubieniecki KL, Johnson LC, Poliektov NE, Bispham NZ, Woodward KA, Nagy EE, Bryan NS, Reisz JA, D'Alessandro A, Chonchol M, Sindler AL, Seals DR. Inorganic Nitrite Supplementation Improves Endothelial Function With Aging: Translational Evidence for Suppression of Mitochondria-Derived Oxidative Stress. Hypertension. 2021 04; 77(4):1212-1222.
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Mudan A, Repplinger D, Lebin J, Lewis J, Vohra R, Smollin C. Severe Methemoglobinemia and Death From Intentional Sodium Nitrite Ingestions. J Emerg Med. 2020 Sep; 59(3):e85-e88.
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McDaniel CT, Panmanee W, Winsor GL, Gill E, Bertelli C, Schurr MJ, Dongare P, Paul AT, Ko SB, Lau GW, Dasgupta N, Bogue AL, Miller WE, Mortensen JE, Haslam DB, Dexheimer P, Muruve DA, Aronow BJ, Forbes MDE, Danilczuk M, Brinkman FSL, Hancock REW, Meyer TJ, Hassett DJ. AB569, a nontoxic chemical tandem that kills major human pathogenic bacteria. Proc Natl Acad Sci U S A. 2020 03 03; 117(9):4921-4930.
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Bebarta VS, Brittain M, Chan A, Garrett N, Yoon D, Burney T, Mukai D, Babin M, Pilz RB, Mahon SB, Brenner M, Boss GR. Sodium Nitrite and Sodium Thiosulfate Are Effective Against Acute Cyanide Poisoning When Administered by Intramuscular Injection. Ann Emerg Med. 2017 Jun; 69(6):718-725.e4.
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Colburn TD, Ferguson SK, Holdsworth CT, Craig JC, Musch TI, Poole DC. Effect of sodium nitrite on local control of contracting skeletal muscle microvascular oxygen pressure in healthy rats. J Appl Physiol (1985). 2017 01 01; 122(1):153-160.
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DeVan AE, Johnson LC, Brooks FA, Evans TD, Justice JN, Cruickshank-Quinn C, Reisdorph N, Bryan NS, McQueen MB, Santos-Parker JR, Chonchol MB, Bassett CJ, Sindler AL, Giordano T, Seals DR. Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults. J Appl Physiol (1985). 2016 Feb 15; 120(4):416-25.
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Justice JN, Johnson LC, DeVan AE, Cruickshank-Quinn C, Reisdorph N, Bassett CJ, Evans TD, Brooks FA, Bryan NS, Chonchol MB, Giordano T, McQueen MB, Seals DR. Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: a pilot trial in middle-aged and older adults. Aging (Albany NY). 2015 Nov; 7(11):1004-21.
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Glean AA, Ferguson SK, Holdsworth CT, Colburn TD, Wright JL, Fees AJ, Hageman KS, Poole DC, Musch TI. Effects of nitrite infusion on skeletal muscle vascular control during exercise in rats with chronic heart failure. Am J Physiol Heart Circ Physiol. 2015 Oct; 309(8):H1354-60.
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Sindler AL, Cox-York K, Reese L, Bryan NS, Seals DR, Gentile CL. Oral nitrite therapy improves vascular function in diabetic mice. Diab Vasc Dis Res. 2015 May; 12(3):221-4.
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