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A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists.

Lyons DS, Lieberman SA, Hampl J, Boniface JJ, Chien Y, Berg LJ, Davis MM. A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. Immunity. 1996 Jul; 5(1):53-61.

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