 Pentose Phosphate Pathway
"Pentose Phosphate Pathway" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An oxidative decarboxylation process that converts GLUCOSE-6-PHOSPHATE to D-ribose-5-phosphate via 6-phosphogluconate. The pentose product is used in the biosynthesis of NUCLEIC ACIDS. The generated energy is stored in the form of NADPH. This pathway is prominent in tissues which are active in the synthesis of FATTY ACIDS and STEROIDS.
| Descriptor ID |
D010427
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| MeSH Number(s) |
G02.111.158.875 G03.191.875 G03.295.693 G03.493.695
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| Concept/Terms |
Pentose Phosphate Pathway- Pentose Phosphate Pathway
- Pathway, Pentose Phosphate
- Pathways, Pentose Phosphate
- Pentose Phosphate Pathways
- Pentose Phosphate Shunt
- Pentose Phosphate Shunts
- Shunt, Pentose Phosphate
- Shunts, Pentose Phosphate
- Pentose Shunt
- Pentose Shunts
- Shunt, Pentose
- Shunts, Pentose
- Pentose-Phosphate Pathway
- Pathway, Pentose-Phosphate
- Pathways, Pentose-Phosphate
- Pentose-Phosphate Pathways
- Pentosephosphate Shunt
- Pentosephosphate Shunts
- Shunt, Pentosephosphate
- Shunts, Pentosephosphate
- Hexose Monophosphate Shunt
- Hexose Monophosphate Shunts
- Shunt, Hexose Monophosphate
- Shunts, Hexose Monophosphate
- Pentosephosphate Pathway
- Pathway, Pentosephosphate
- Pathways, Pentosephosphate
- Pentosephosphate Pathways
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Below are MeSH descriptors whose meaning is more general than "Pentose Phosphate Pathway".
Below are MeSH descriptors whose meaning is more specific than "Pentose Phosphate Pathway".
This graph shows the total number of publications written about "Pentose Phosphate Pathway" by people in this website by year, and whether "Pentose Phosphate Pathway" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 1 | 2 | | 2013 | 0 | 2 | 2 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 2 | 3 | | 2017 | 0 | 4 | 4 | | 2018 | 0 | 2 | 2 | | 2019 | 0 | 2 | 2 | | 2020 | 1 | 2 | 3 | | 2021 | 0 | 3 | 3 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pentose Phosphate Pathway" by people in Profiles.
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Ohm AM, Affandi T, Reisz JA, Caino MC, D'Alessandro A, Reyland ME. Metabolic reprogramming contributes to radioprotection by protein kinase Cd. J Biol Chem. 2023 10; 299(10):105186.
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Sake CL, Metcalf AJ, Meagher M, Di Paola J, Neeves KB, Boyle NR. Isotopically nonstationary 13C metabolic flux analysis in resting and activated human platelets. Metab Eng. 2022 01; 69:313-322.
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Issaian A, Hay A, Dzieciatkowska M, Roberti D, Perrotta S, Darula Z, Redzic J, Busch MP, Page GP, Rogers SC, Doctor A, Hansen KC, Eisenmesser EZ, Zimring JC, D'Alessandro A. The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality. Haematologica. 2021 Nov 01; 106(11):2971-2985.
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Cano M, Datta S, Wang L, Liu T, Flores-Bellver M, Sachdeva M, Sinha D, Handa JT. Nrf2 deficiency decreases NADPH from impaired IDH shuttle and pentose phosphate pathway in retinal pigmented epithelial cells to magnify oxidative stress-induced mitochondrial dysfunction. Aging Cell. 2021 08; 20(8):e13444.
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Alexander K, Hazegh K, Fang F, Sinchar D, Kiss JE, Page GP, D'Alessandro A, Kanias T. Testosterone replacement therapy in blood donors modulates erythrocyte metabolism and susceptibility to hemolysis in cold storage. Transfusion. 2021 01; 61(1):108-123.
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D'Alessandro A, Fu X, Reisz JA, Kanias T, Page GP, Stone M, Kleinman S, Zimring JC, Busch M. Stored RBC metabolism as a function of caffeine levels. Transfusion. 2020 06; 60(6):1197-1211.
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Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB. Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. Sci Rep. 2020 01 15; 10(1):413.
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Gehrke S, Shah N, Gamboni F, Kamyszek R, Srinivasan AJ, Gray A, Landrigan M, Welsby I, D'Alessandro A. Metabolic impact of red blood cell exchange with rejuvenated red blood cells in sickle cell patients. Transfusion. 2019 10; 59(10):3102-3112.
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Chen Y, Manna SK, Golla S, Krausz KW, Cai Y, Garcia-Milian R, Chakraborty T, Chakraborty J, Chatterjee R, Thompson DC, Gonzalez FJ, Vasiliou V. Glutathione deficiency-elicited reprogramming of hepatic metabolism protects against alcohol-induced steatosis. Free Radic Biol Med. 2019 11 01; 143:127-139.
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Szwarc MM, Kommagani R, Putluri V, Dubrulle J, Stossi F, Mancini MA, Coarfa C, Lanz RB, Putluri N, DeMayo FJ, Lydon JP, O'Malley BW. Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells. Sci Rep. 2018 09 03; 8(1):13134.
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