Hydroxyzine
"Hydroxyzine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
Descriptor ID |
D006919
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MeSH Number(s) |
D03.383.606.515
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Concept/Terms |
Hydroxyzine- Hydroxyzine
- 2-(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol
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Below are MeSH descriptors whose meaning is more general than "Hydroxyzine".
Below are MeSH descriptors whose meaning is more specific than "Hydroxyzine".
This graph shows the total number of publications written about "Hydroxyzine" by people in this website by year, and whether "Hydroxyzine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 0 | 1 | 1 | 2022 | 0 | 1 | 1 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hydroxyzine" by people in Profiles.
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Simon M, Heard K. Are antimuscarinic effects common in hydroxyzine overdose? A cohort analysis of antimuscarinic effects in hydroxyzine and diphenhydramine-poisoned patients. Clin Toxicol (Phila). 2023 05; 61(5):379-386.
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Morrow RL, Mintzes B, Souverein PC, Hallgreen CE, Ahmed B, Roughead EE, De Bruin ML, Kristiansen SB, Lexchin J, Kemp-Casey A, Sketris I, Mangin D, Pearson SA, Puil L, Lopert R, Bero L, Gnjidic D, Sarpatwari A, Dormuth CR. Hydroxyzine Initiation Following Drug Safety Advisories on Cardiac Arrhythmias in the UK and Canada: A Longitudinal Cohort Study. Drug Saf. 2022 06; 45(6):623-638.
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Dosani FZ, Flaitz CM, Whitmire HC, Vance BJ, Hill JR. Postdischarge events occurring after pediatric sedation for dentistry. Pediatr Dent. 2014 Sep-Oct; 36(5):411-6.
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Davis RS, Remigio LK, Schocket AL, Bock SA. Evaluation of a patient with both aquagenic and cholinergic urticaria. J Allergy Clin Immunol. 1981 Dec; 68(6):479-83.
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Harvey RP, Wegs J, Schocket AL. A controlled trial of therapy in chronic urticaria. J Allergy Clin Immunol. 1981 Oct; 68(4):262-6.
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Harvey RP, Schocket AL. The effect of H1 and H2 blockade on cutaneous histamine response in man. J Allergy Clin Immunol. 1980 Feb; 65(2):136-9.
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