 Cytochalasin D
"Cytochalasin D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release.
| Descriptor ID |
D015638
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| MeSH Number(s) |
D03.633.100.473.231.450 D23.946.587.370.450
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytochalasin D".
Below are MeSH descriptors whose meaning is more specific than "Cytochalasin D".
This graph shows the total number of publications written about "Cytochalasin D" by people in this website by year, and whether "Cytochalasin D" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytochalasin D" by people in Profiles.
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Coakley G, McCaskill JL, Borger JG, Simbari F, Robertson E, Millar M, Harcus Y, McSorley HJ, Maizels RM, Buck AH. Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity. Cell Rep. 2017 05 23; 19(8):1545-1557.
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Lanzicher T, Martinelli V, Puzzi L, Del Favero G, Codan B, Long CS, Mestroni L, Taylor MR, Sbaizero O. The Cardiomyopathy Lamin A/C D192G Mutation Disrupts Whole-Cell Biomechanics in Cardiomyocytes as Measured by Atomic Force Microscopy Loading-Unloading Curve Analysis. Sci Rep. 2015 Sep 01; 5:13388.
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Sbaizero O, DelFavero G, Martinelli V, Long CS, Mestroni L. Analysis of long- and short-range contribution to adhesion work in cardiac fibroblasts: an atomic force microscopy study. Mater Sci Eng C Mater Biol Appl. 2015 Apr; 49:217-224.
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Charest-Morin X, Fortin S, Lodge R, Roy C, Gera L, Gaudreault RC, Marceau F. Inhibitory effects of cytoskeleton disrupting drugs and GDP-locked Rab mutants on bradykinin B2 receptor cycling. Pharmacol Res. 2013 May; 71:44-52.
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Atkinson SJ, Hosford MA, Molitoris BA. Mechanism of actin polymerization in cellular ATP depletion. J Biol Chem. 2004 Feb 13; 279(7):5194-9.
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Haendel MA, Bollinger KE, Baas PW. Cytoskeletal changes during neurogenesis in cultures of avain neural crest cells. J Neurocytol. 1996 Apr; 25(4):289-301.
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Doedens J, Maynell LA, Klymkowsky MW, Kirkegaard K. Secretory pathway function, but not cytoskeletal integrity, is required in poliovirus infection. Arch Virol Suppl. 1994; 9:159-72.
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Schliwa M, van Blerkom J, Pryzwansky KB. Structural organization of the cytoplasm. Cold Spring Harb Symp Quant Biol. 1982; 46 Pt 1:51-67.
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