The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis.
Shen C, Liu Y, Yu H, Gulbranson DR, Kogut I, Bilousova G, Zhang C, Stowell MHB, Shen J. The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis. J Biol Chem. 2018 11 23; 293(47):18309-18317.