 Amitriptyline
"Amitriptyline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
| Descriptor ID |
D000639
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| MeSH Number(s) |
D02.455.426.559.847.181.384.100 D04.615.181.384.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Amitriptyline".
Below are MeSH descriptors whose meaning is more specific than "Amitriptyline".
This graph shows the total number of publications written about "Amitriptyline" by people in this website by year, and whether "Amitriptyline" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 1999 | 2 | 0 | 2 | | 2001 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Amitriptyline" by people in Profiles.
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Radi R, Huang H, Rivera J, Lyon C, DeSanto K. Is low-dose naltrexone effective in chronic pain management? J Fam Pract. 2023 09; 72(7):320-321.
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Finch PM, Drummond PD. Topical treatment in pain medicine: from ancient remedies to modern usage. Pain Manag. 2015 Sep; 5(5):359-71.
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Chua-Tuan JL, Cao D, Iwanicki JL, Hoyte CO. Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report. Clin Toxicol (Phila). 2015 Jul; 53(6):565-8.
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Zoladz PR, Fleshner M, Diamond DM. Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 01; 44:1-16.
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Bebarta VS, Maddry J, Borys DJ, Morgan DL. Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose. Am J Emerg Med. 2012 Feb; 30(2):374.
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Bebarta VS, Maddry J, Borys DJ, Morgan DL. Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose. Am J Emerg Med. 2011 Jul; 29(6):645-9.
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Menard-Katcher C, Henretig FM, Osterhoudt KC. A 19-month-old girl with recurrent illness: over the hills and through the woods. Pediatr Emerg Care. 2009 Dec; 25(12):869-71.
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Billups SJ, Delate T, Dugan D. Evaluation of risk factors for elevated tricyclic antidepressant plasma concentrations. Pharmacoepidemiol Drug Saf. 2009 Mar; 18(3):253-7.
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Bebarta VS, Waksman JC. Reply to: "Amitriptyline-induced Brugada pattern fails to respond to sodium bicarbonate". Clin Toxicol (Phila). 2008 Jan; 46(1):90-1.
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Bebarta VS, Waksman JC. Amitriptyline-induced Brugada pattern fails to respond to sodium bicarbonate. Clin Toxicol (Phila). 2007; 45(2):186-8.
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