 E2F4 Transcription Factor
"E2F4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F4 recruits chromatin remodeling factors indirectly to target gene PROMOTER REGIONS through RETINOBLASTOMA LIKE PROTEIN P130 and RETINOBLASTOMA LIKE PROTEIN P107.
| Descriptor ID |
D050704
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| MeSH Number(s) |
D12.776.930.211.812
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| Concept/Terms |
E2F4 Transcription Factor- E2F4 Transcription Factor
- Transcription Factor, E2F4
- E2F-4 Transcription Factor
- E2F 4 Transcription Factor
- Transcription Factor, E2F-4
- E2F Transcription Factor 4 Protein
- E2F-4 Protein
- E2F 4 Protein
- Transcription Factor E2F-4
- E2F-4, Transcription Factor
- Transcription Factor E2F 4
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Below are MeSH descriptors whose meaning is more general than "E2F4 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F4 Transcription Factor".
This graph shows the total number of publications written about "E2F4 Transcription Factor" by people in this website by year, and whether "E2F4 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "E2F4 Transcription Factor" by people in Profiles.
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Deng Y, Liu J, Han G, Lu SL, Wang SY, Malkoski S, Tan AC, Deng C, Wang XJ, Zhang Q. Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1. Oncogene. 2010 Dec 16; 29(50):6603-8.
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Rempel RE, Mori S, Gasparetto M, Glozak MA, Andrechek ER, Adler SB, Laakso NM, Lagoo AS, Storms R, Smith C, Nevins JR. A role for E2F activities in determining the fate of Myc-induced lymphomagenesis. PLoS Genet. 2009 Sep; 5(9):e1000640.
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Ozono E, Komori H, Iwanaga R, Ikeda MA, Iseki S, Ohtani K. E2F-like elements in p27(Kip1) promoter specifically sense deregulated E2F activity. Genes Cells. 2009 Jan; 14(1):89-99.
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Lucas JJ, Domenico J, Gelfand EW. Cyclin-dependent kinase 6 inhibits proliferation of human mammary epithelial cells. Mol Cancer Res. 2004 Feb; 2(2):105-14.
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Singh RP, Agarwal C, Agarwal R. Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes. Carcinogenesis. 2003 Mar; 24(3):555-63.
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Fry CJ, Slansky JE, Farnham PJ. Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain. Mol Cell Biol. 1997 Apr; 17(4):1966-76.
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