E2F6 Transcription Factor
"E2F6 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F6 recruits chromatin remodeling factors directly to target gene promoters and lacks the transactivation domain responsible for binding to the retinoblastoma family of tumor suppressors.
| Descriptor ID |
D050701
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| MeSH Number(s) |
D12.776.930.211.937
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| Concept/Terms |
E2F6 Transcription Factor- E2F6 Transcription Factor
- Transcription Factor, E2F6
- Transcription Factor E2F-6
- E2F-6, Transcription Factor
- Transcription Factor E2F 6
- E2F Transcription Factor 6 Protein
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Below are MeSH descriptors whose meaning is more general than "E2F6 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F6 Transcription Factor".
This graph shows the total number of publications written about "E2F6 Transcription Factor" by people in this website by year, and whether "E2F6 Transcription Factor" was a major or minor topic of these publications.
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Below are the most recent publications written about "E2F6 Transcription Factor" by people in Profiles.
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Major JL, Salih M, Tuana BS. E2F6 protein levels modulate drug induced apoptosis in cardiomyocytes. Cell Signal. 2017 12; 40:230-238.
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Major JL, Dewan A, Salih M, Leddy JJ, Tuana BS. E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy. PLoS One. 2017; 12(1):e0170066.
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Major JL, Salih M, Tuana BS. Interplay between the E2F pathway and ?-adrenergic signaling in the pathological hypertrophic response of myocardium. J Mol Cell Cardiol. 2015 Jul; 84:179-90.
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Westendorp B, Major JL, Nader M, Salih M, Leenen FH, Tuana BS. The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy. FASEB J. 2012 Jun; 26(6):2569-79.