Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation.

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Abietane-Type Diterpen

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Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation.

Hjortness MK, Riccardi L, Hongdusit A, Ruppe S, Zhao M, Kim EY, Zwart PH, Sankaran B, Arthanari H, Sousa MC, De Vivo M, Fox JM. Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation. Biochemistry. 2018 10 09; 57(40):5886-5896.

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subject areas

Humans
Models, Molecular
Molecular Dynamics Simulation
Nuclear Magnetic Resonance, Biomolecular
Protein Domains
Protein Folding
Protein Kinase Inhibitors
Protein Tyrosine Phosphatase, Non-Receptor Type 1

authors with profiles

Jerome Michael Fox
Marcelo Carlos Sousa

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