 Methemoglobinemia
"Methemoglobinemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Descriptor ID |
D008708
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| MeSH Number(s) |
C15.378.619
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methemoglobinemia".
Below are MeSH descriptors whose meaning is more specific than "Methemoglobinemia".
This graph shows the total number of publications written about "Methemoglobinemia" by people in this website by year, and whether "Methemoglobinemia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Methemoglobinemia" by people in Profiles.
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Mudan A, Repplinger D, Lebin J, Lewis J, Vohra R, Smollin C. Severe Methemoglobinemia and Death From Intentional Sodium Nitrite Ingestions. J Emerg Med. 2020 Sep; 59(3):e85-e88.
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Jiwani AZ, Bebarta VS, Cancio LC. Acquired methemoglobinemia after hydroxocobalamin administration in a patient with burns and inhalation injury. Clin Toxicol (Phila). 2018 05; 56(5):370-372.
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Baek JH, Zhang X, Williams MC, Hicks W, Buehler PW, D'Agnillo F. Sodium nitrite potentiates renal oxidative stress and injury in hemoglobin exposed guinea pigs. Toxicology. 2015 Jul 03; 333:89-99.
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DomBourian M, Ezhuthachan A, Kohn A, Berman B, Sykes E. A 5-hour-old male neonate with cyanosis. Lab Med. 2015; 46(1):60-3; quiz e14.
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Larson A, Stidham T, Banerji S, Kaufman J. Seizures and methemoglobinemia in an infant after excessive EMLA application. Pediatr Emerg Care. 2013 Mar; 29(3):377-9.
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Sankoff J, Louie AD. Clinicopathologic conference: a 28-year-old woman with perioral cyanosis and low oxygen saturation. Acad Emerg Med. 2008 Apr; 15(4):363-7.
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Dunne J, Caron A, Menu P, Alayash AI, Buehler PW, Wilson MT, Silaghi-Dumitrescu R, Faivre B, Cooper CE. Ascorbate removes key precursors to oxidative damage by cell-free haemoglobin in vitro and in vivo. Biochem J. 2006 Nov 01; 399(3):513-24.
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Murone AJ, Stucki P, Roback MG, Gehri M. Severe methemoglobinemia due to food intoxication in infants. Pediatr Emerg Care. 2005 Aug; 21(8):536-8.
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Janssen WJ, Dhaliwal G, Collard HR, Saint S. Clinical problem-solving. Why "why" matters. N Engl J Med. 2004 Dec 02; 351(23):2429-34.
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Hall AH, Kulig KW, Rumack BH. Drug- and chemical-induced methaemoglobinaemia. Clinical features and management. Med Toxicol. 1986 Jul-Aug; 1(4):253-60.
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