 Phospholipase D
"Phospholipase D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme found mostly in plant tissue. It hydrolyzes glycerophosphatidates with the formation of a phosphatidic acid and a nitrogenous base such as choline. This enzyme also catalyzes transphosphatidylation reactions. EC 3.1.4.4.
| Descriptor ID |
D010739
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| MeSH Number(s) |
D08.811.277.352.640.700.710
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| Concept/Terms |
Phospholipase D- Phospholipase D
- Lecithinase D
- Phosphatidylcholine Phosphohydrolase
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Below are MeSH descriptors whose meaning is more general than "Phospholipase D".
Below are MeSH descriptors whose meaning is more specific than "Phospholipase D".
This graph shows the total number of publications written about "Phospholipase D" by people in this website by year, and whether "Phospholipase D" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phospholipase D" by people in Profiles.
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Angeletti A, Cantarelli C, Petrosyan A, Andrighetto S, Budge K, D'Agati VD, Hartzell S, Malvi D, Donadei C, Thurman JM, Gale?ic-Ljubanovic D, He JC, Xiao W, Campbell KN, Wong J, Fischman C, Manrique J, Zaza G, Fiaccadori E, La Manna G, Fribourg M, Leventhal J, Da Sacco S, Perin L, Heeger PS, Cravedi P. Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis. J Exp Med. 2020 09 07; 217(9).
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Coit P, Kaushik P, Caplan L, Kerr GS, Walsh JA, Dubreuil M, Reimold A, Sawalha AH. Genome-wide DNA methylation analysis in ankylosing spondylitis identifies HLA-B*27 dependent and independent DNA methylation changes in whole blood. J Autoimmun. 2019 08; 102:126-132.
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Stith BJ. Phospholipase C and D regulation of Src, calcium release and membrane fusion during Xenopus laevis development. Dev Biol. 2015 May 15; 401(2):188-205.
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Peters DM, Vad?sz I, Wujak L, Wygrecka M, Olschewski A, Becker C, Herold S, Papp R, Mayer K, Rummel S, Brandes RP, G?nther A, Waldegger S, Eickelberg O, Seeger W, Morty RE. TGF-? directs trafficking of the epithelial sodium channel ENaC which has implications for ion and fluid transport in acute lung injury. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):E374-83.
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Kent DG, Copley MR, Benz C, W?hrer S, Dykstra BJ, Ma E, Cheyne J, Zhao Y, Bowie MB, Zhao Y, Gasparetto M, Delaney A, Smith C, Marra M, Eaves CJ. Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential. Blood. 2009 Jun 18; 113(25):6342-50.
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Wilderman PJ, Vasil AI, Johnson Z, Vasil ML. Genetic and biochemical analyses of a eukaryotic-like phospholipase D of Pseudomonas aeruginosa suggest horizontal acquisition and a role for persistence in a chronic pulmonary infection model. Mol Microbiol. 2001 Jan; 39(2):291-303.
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Cheng J, Weber JD, Baldassare JJ, Raben DM. Ablation of Go alpha-subunit results in a transformed phenotype and constitutively active phosphatidylcholine-specific phospholipase C. J Biol Chem. 1997 Jul 11; 272(28):17312-9.
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Stith BJ, Goalstone ML, Espinoza R, Mossel C, Roberts D, Wiernsperger N. The antidiabetic drug metformin elevates receptor tyrosine kinase activity and inositol 1,4,5-trisphosphate mass in Xenopus oocytes. Endocrinology. 1996 Jul; 137(7):2990-9.
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Jones GW, Ashwood ER. Enzymatic measurement of phosphatidylglycerol in amniotic fluid. Clin Chem. 1994 Apr; 40(4):518-25.
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Wright TM, Willenberger S, Raben DM. Activation of phospholipase D by alpha-thrombin or epidermal growth factor contributes to the formation of phosphatidic acid, but not to observed increases in 1,2-diacylglycerol. Biochem J. 1992 Jul 15; 285 ( Pt 2):395-400.
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