alpha-Tocopherol
"alpha-Tocopherol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.
Descriptor ID |
D024502
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MeSH Number(s) |
D03.383.663.283.909.750.249 D03.633.100.150.909.750.249
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Concept/Terms |
alpha-Tocopherol- alpha-Tocopherol
- alpha Tocopherol
- 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
alpha-Tocopherol Acetate- alpha-Tocopherol Acetate
- alpha Tocopherol Acetate
- Tocopheryl Acetate
- Tocopherol Acetate
- Acetate, Tocopherol
alpha-Tocopherol Succinate- alpha-Tocopherol Succinate
- alpha Tocopherol Succinate
- Tocopherol Succinate
- Succinate, Tocopherol
- alpha-Tocopherol Hemisuccinate
- alpha Tocopherol Hemisuccinate
d-alpha Tocopherol- d-alpha Tocopherol
- Tocopherol, d-alpha
- d alpha Tocopherol
- R,R,R-alpha-Tocopherol
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Below are MeSH descriptors whose meaning is more general than "alpha-Tocopherol".
Below are MeSH descriptors whose meaning is more specific than "alpha-Tocopherol".
This graph shows the total number of publications written about "alpha-Tocopherol" by people in this website by year, and whether "alpha-Tocopherol" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 3 | 3 | 2005 | 1 | 0 | 1 | 2006 | 1 | 0 | 1 | 2008 | 1 | 2 | 3 | 2010 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2016 | 1 | 0 | 1 | 2018 | 1 | 1 | 2 | 2019 | 1 | 0 | 1 | 2020 | 2 | 1 | 3 | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "alpha-Tocopherol" by people in Profiles.
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Jeon S, Li Q, Ranard KM, Rubakhin SS, Sweedler JV, Kuchan MJ, Erdman JW. Spatiotemporal biodistribution of a-tocopherol is impacted by the source of 13C-labeled a-tocopherol in mice following a single oral dose. Nutr Res. 2021 09; 93:79-86.
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Kuchan MJ, Ranard KM, Dey P, Jeon S, Sasaki GY, Schimpf KJ, Bruno RS, Neuringer M, Erdman JW. Infant Rhesus Macaque Brain a-Tocopherol Stereoisomer Profile Is Differentially Impacted by the Source of a-Tocopherol in Infant Formula. J Nutr. 2020 09 01; 150(9):2305-2313.
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Ranard KM, Kuchan MJ, Bruno RS, Juraska JM, Erdman JW. Synthetic a-Tocopherol, Compared with Natural a-Tocopherol, Downregulates Myelin Genes in Cerebella of Adolescent Ttpa-null Mice. J Nutr. 2020 05 01; 150(5):1031-1040.
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Mandil R, Prakash A, Rahal A, Singh SP, Sharma D, Kumar R, Garg SK. In vitro and in vivo effects of flubendiamide and copper on cyto-genotoxicity, oxidative stress and spleen histology of rats and its modulation by resveratrol, catechin, curcumin and a-tocopherol. BMC Pharmacol Toxicol. 2020 04 23; 21(1):29.
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Ranard KM, Kuchan MJ, Erdman JW. a-Tocopherol, but Not ?-Tocopherol, Attenuates the Expression of Selective Tumor Necrosis Factor-Alpha-Induced Genes in Primary Human Aortic Cell Lines. Lipids. 2019 05; 54(5):289-299.
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Ranard KM, Erdman JW. Authors' Reply: Comparison of different vitamin E forms is confounded by heterogeneity in vitamin E effects. Nutr Rev. 2018 09 01; 76(9):724.
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Ranard KM, Erdman JW. Effects of dietary RRR a-tocopherol vs all-racemic a-tocopherol on health outcomes. Nutr Rev. 2018 03 01; 76(3):141-153.
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Mandil R, Rahal A, Prakash A, Garg SK, Gangwar NK, Swain DK. Ameliorative potential of a-tocopherol against flubendiamide and copper-induced testicular-insult in Wistar rats. Chem Biol Interact. 2016 Dec 25; 260:91-101.
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Ervin RB, Dye BA. Associations between posterior functional contacts and nutrient intakes and serum nutrient values among adults in NHANES 2003-2004. Oral Health Prev Dent. 2014; 12(3):265-76.
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Shneider BL, Magee JC, Bezerra JA, Haber B, Karpen SJ, Raghunathan T, Rosenthal P, Schwarz K, Suchy FJ, Kerkar N, Turmelle Y, Whitington PF, Robuck PR, Sokol RJ. Efficacy of fat-soluble vitamin supplementation in infants with biliary atresia. Pediatrics. 2012 Sep; 130(3):e607-14.
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