Quinine
"Quinine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
Descriptor ID |
D011803
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MeSH Number(s) |
D03.132.206.719 D03.605.687.762 D03.633.100.810.762
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Concept/Terms |
Quinine Sulfate- Quinine Sulfate
- Sulfate, Quinine
- Quinine Sulphate
- Sulphate, Quinine
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Below are MeSH descriptors whose meaning is more general than "Quinine".
Below are MeSH descriptors whose meaning is more specific than "Quinine".
This graph shows the total number of publications written about "Quinine" by people in this website by year, and whether "Quinine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 1 | 2 | 1998 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2009 | 0 | 2 | 2 | 2017 | 0 | 1 | 1 | 2019 | 4 | 0 | 4 | 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Quinine" by people in Profiles.
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Vandenbeuch A, Wilson CE, Kinnamon SC. Optogenetic Activation of Type III Taste Cells Modulates Taste Responses. Chem Senses. 2020 10 09; 45(7):533-539.
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Martin LE, Kay KE, James KF, Torregrossa AM. Altering salivary protein profile can decrease aversive oromotor responding to quinine in rats. Physiol Behav. 2020 09 01; 223:113005.
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Voelker L, Upadhyaya B, Ferkey DM, Woldemariam S, L'Etoile ND, Rabinowitch I, Bai J. INX-18 and INX-19 play distinct roles in electrical synapses that modulate aversive behavior in Caenorhabditis elegans. PLoS Genet. 2019 10; 15(10):e1008341.
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Martin LE, Kay KE, Torregrossa AM. Rats are unable to discriminate quinine from diverse bitter stimuli. Am J Physiol Regul Integr Comp Physiol. 2019 12 01; 317(6):R793-R802.
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Martin LE, Kay KE, Torregrossa AM. Bitter-Induced Salivary Proteins Increase Detection Threshold of Quinine, But Not Sucrose. Chem Senses. 2019 07 17; 44(6):379-388.
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Martin LE, Nikonova LV, Kay KE, Torregrossa AM. Altering salivary protein profile can increase acceptance of a novel bitter diet. Appetite. 2019 05 01; 136:8-17.
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Young DS, Miller ES, Bhatia K. Fever and Malaise in an Infant. J Emerg Med. 2017 Aug; 53(2):265-268.
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Hallock RM, Tatangelo M, Barrows J, Finger TE. Residual chemosensory capabilities in double P2X2/P2X3 purinergic receptor null mice: intraoral or postingestive detection? Chem Senses. 2009 Nov; 34(9):799-808.
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Stratford JM, Contreras RJ. Saliva and other taste stimuli are important for gustatory processing of linoleic acid. Am J Physiol Regul Integr Comp Physiol. 2009 Oct; 297(4):R1162-70.
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Bachtell RK, Weitemier AZ, Ryabinin AE. Lesions of the Edinger-Westphal nucleus in C57BL/6J mice disrupt ethanol-induced hypothermia and ethanol consumption. Eur J Neurosci. 2004 Sep; 20(6):1613-23.
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