 Tissue Inhibitor of Metalloproteinase-1
"Tissue Inhibitor of Metalloproteinase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro.
| Descriptor ID |
D019715
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| MeSH Number(s) |
D12.776.645.875.450
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tissue Inhibitor of Metalloproteinase-1".
Below are MeSH descriptors whose meaning is more specific than "Tissue Inhibitor of Metalloproteinase-1".
This graph shows the total number of publications written about "Tissue Inhibitor of Metalloproteinase-1" by people in this website by year, and whether "Tissue Inhibitor of Metalloproteinase-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2004 | 0 | 1 | 1 | | 2005 | 1 | 2 | 3 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 2 | 2 | | 2008 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2019 | 1 | 2 | 3 | | 2022 | 1 | 1 | 2 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tissue Inhibitor of Metalloproteinase-1" by people in Profiles.
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Mack TM, Raddatz MA, Pershad Y, Nachun DC, Taylor KD, Guo X, Shuldiner AR, O'Connell JR, Kenny EE, Loos RJF, Redline S, Cade BE, Psaty BM, Bis JC, Brody JA, Silverman EK, Yun JH, Cho MH, DeMeo DL, Levy D, Johnson AD, Mathias RA, Yanek LR, Heckbert SR, Smith NL, Wiggins KL, Raffield LM, Carson AP, Rotter JI, Rich SS, Manichaikul AW, Gu CC, Chen YI, Lee WJ, Shoemaker MB, Roden DM, Kooperberg C, Auer PL, Desai P, Blackwell TW, Smith AV, Reiner AP, Jaiswal S, Weinstock JS, Bick AG. Epigenetic and proteomic signatures associate with clonal hematopoiesis expansion rate. Nat Aging. 2024 Aug; 4(8):1043-1052.
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Frank BS, Nandy D, Khailova L, Mitchell MB, Morgan GJ, Twite M, DiMaria MV, Davidson JA. Circulating biomarkers of extracellular matrix dysregulation are associated with adverse post-stage 2 outcomes in infants with single ventricle heart disease. Sci Rep. 2023 09 28; 13(1):16318.
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Rao VV, Wechsler ME, Cravens E, Wojda SJ, Caldwell AS, Kirkpatrick BE, Donahue SW, Anseth KS. Granular PEG hydrogels mediate osteoporotic MSC clustering via N-cadherin influencing the pro-resorptive bias of their secretory profile. Acta Biomater. 2022 06; 145:77-87.
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Raeeszadeh-Sarmazdeh M, Coban M, Mahajan S, Hockla A, Sankaran B, Downey GP, Radisky DC, Radisky ES. Engineering of tissue inhibitor of metalloproteinases TIMP-1 for fine discrimination between closely related stromelysins MMP-3 and MMP-10. J Biol Chem. 2022 03; 298(3):101654.
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Rodriguez-Pla A, Warner RL, Cuthbertson D, Carette S, Khalidi NA, Koening CL, Langford CA, McAlear CA, Moreland LW, Pagnoux C, Seo P, Specks U, Sreih AG, Ytterberg SR, Johnson KJ, Merkel PA, Monach PA. Evaluation of Potential Serum Biomarkers of Disease Activity in Diverse Forms of Vasculitis. J Rheumatol. 2020 07 01; 47(7):1001-1010.
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Raeeszadeh-Sarmazdeh M, Greene KA, Sankaran B, Downey GP, Radisky DC, Radisky ES. Directed evolution of the metalloproteinase inhibitor TIMP-1 reveals that its N- and C-terminal domains cooperate in matrix metalloproteinase recognition. J Biol Chem. 2019 06 14; 294(24):9476-9488.
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Hodges MM, Zgheib C, Xu J, Hu J, Dewberry LC, Hilton SA, Allukian MW, Gorman JH, Gorman RC, Liechty KW. Differential Expression of Transforming Growth Factor-?1 Is Associated With Fetal Regeneration After Myocardial Infarction. Ann Thorac Surg. 2019 07; 108(1):59-66.
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Xu X, Abdalla T, Bratcher PE, Jackson PL, Sabbatini G, Wells JM, Lou XY, Quinn R, Blalock JE, Clancy JP, Gaggar A. Doxycycline improves clinical outcomes during cystic fibrosis exacerbations. Eur Respir J. 2017 04; 49(4).
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Vogel ER, Britt RD, Faksh A, Kuipers I, Pandya H, Prakash YS, Martin RJ, Pabelick CM. Moderate hyperoxia induces extracellular matrix remodeling by human fetal airway smooth muscle cells. Pediatr Res. 2017 02; 81(2):376-383.
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Shi J, Dai W, Hale SL, Brown DA, Wang M, Han X, Kloner RA. Bendavia restores mitochondrial energy metabolism gene expression and suppresses cardiac fibrosis in the border zone of the infarcted heart. Life Sci. 2015 Nov 15; 141:170-8.
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