Glycyrrhizic Acid
"Glycyrrhizic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.
Descriptor ID |
D019695
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MeSH Number(s) |
D02.455.849.919.530.466
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Concept/Terms |
Glycyrrhizic Acid- Glycyrrhizic Acid
- Acid, Glycyrrhizic
- Glycyrrhizinic Acid
- Acid, Glycyrrhizinic
- Glycyrrhizin
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Below are MeSH descriptors whose meaning is more general than "Glycyrrhizic Acid".
Below are MeSH descriptors whose meaning is more specific than "Glycyrrhizic Acid".
This graph shows the total number of publications written about "Glycyrrhizic Acid" by people in this website by year, and whether "Glycyrrhizic Acid" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 | 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glycyrrhizic Acid" by people in Profiles.
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Gumpricht E, Dahl R, Devereaux MW, Sokol RJ. Licorice compounds glycyrrhizin and 18beta-glycyrrhetinic acid are potent modulators of bile acid-induced cytotoxicity in rat hepatocytes. J Biol Chem. 2005 Mar 18; 280(11):10556-63.
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Spataro LE, Sloane EM, Milligan ED, Wieseler-Frank J, Schoeniger D, Jekich BM, Barrientos RM, Maier SF, Watkins LR. Spinal gap junctions: potential involvement in pain facilitation. J Pain. 2004 Sep; 5(7):392-405.
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Deutchman M, Petrou ID, Mellberg JR. Effect of fluoride and glycyrrhizin mouthrinses on artificial caries lesions in vivo. Caries Res. 1989; 23(3):206-8.
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