Pancreas, Exocrine
"Pancreas, Exocrine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major component (about 80%) of the PANCREAS composed of acinar functional units of tubular and spherical cells. The acinar cells synthesize and secrete several digestive enzymes such as TRYPSINOGEN; LIPASE; AMYLASE; and RIBONUCLEASE. Secretion from the exocrine pancreas drains into the pancreatic ductal system and empties into the DUODENUM.
Descriptor ID |
D046790
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MeSH Number(s) |
A03.734.540 A10.336.645
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pancreas, Exocrine".
Below are MeSH descriptors whose meaning is more specific than "Pancreas, Exocrine".
This graph shows the total number of publications written about "Pancreas, Exocrine" by people in this website by year, and whether "Pancreas, Exocrine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2006 | 2 | 1 | 3 | 2007 | 0 | 1 | 1 | 2008 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pancreas, Exocrine" by people in Profiles.
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Lorberbaum DS, Docherty FM, Sussel L. Animal Models of Pancreas Development, Developmental Disorders, and Disease. Adv Exp Med Biol. 2020; 1236:65-85.
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Khera E, Zhang L, Roberts S, Nessler I, Sandoval D, Reiner T, Thurber GM. Blocking of Glucagonlike Peptide-1 Receptors in the Exocrine Pancreas Improves Specificity for ?-Cells in a Mouse Model of Type 1 Diabetes. J Nucl Med. 2019 11; 60(11):1635-1641.
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Miller MR, Soave D, Li W, Gong J, Pace RG, Bo?lle PY, Cutting GR, Drumm ML, Knowles MR, Sun L, Rommens JM, Accurso F, Durie PR, Corvol H, Levy H, Sontag MK, Strug LJ. Variants in Solute Carrier SLC26A9 Modify Prenatal Exocrine Pancreatic Damage in Cystic Fibrosis. J Pediatr. 2015 May; 166(5):1152-1157.e6.
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Soave D, Miller MR, Keenan K, Li W, Gong J, Ip W, Accurso F, Sun L, Rommens JM, Sontag M, Durie PR, Strug LJ. Evidence for a causal relationship between early exocrine pancreatic disease and cystic fibrosis-related diabetes: a Mendelian randomization study. Diabetes. 2014 Jun; 63(6):2114-9.
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Singhi AD, Norwood S, Liu TC, Sharma R, Wolfgang CL, Schulick RD, Zeh HJ, Hruban RH. Acinar cell cystadenoma of the pancreas: a benign neoplasm or non-neoplastic ballooning of acinar and ductal epithelium? Am J Surg Pathol. 2013 Sep; 37(9):1329-35.
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Habbe N, Shi G, Meguid RA, Fendrich V, Esni F, Chen H, Feldmann G, Stoffers DA, Konieczny SF, Leach SD, Maitra A. Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice. Proc Natl Acad Sci U S A. 2008 Dec 02; 105(48):18913-8.
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Kavitha JV, Rosario JF, Chandran J, Anbu P. Hypoglycemic and other related effects of Boswellia glabra in alloxan-induced diabetic rats. Indian J Physiol Pharmacol. 2007 Jan-Mar; 51(1):29-39.
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Walgren JL, Mitchell MD, Whiteley LO, Thompson DC. Identification of novel peptide safety markers for exocrine pancreatic toxicity induced by cyanohydroxybutene. Toxicol Sci. 2007 Mar; 96(1):174-83.
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Walgren JL, Mitchell MD, Whiteley LO, Thompson DC. Evaluation of two novel peptide safety markers for exocrine pancreatic toxicity. Toxicol Sci. 2007 Mar; 96(1):184-93.
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McManaman JL, Reyland ME, Thrower EC. Secretion and fluid transport mechanisms in the mammary gland: comparisons with the exocrine pancreas and the salivary gland. J Mammary Gland Biol Neoplasia. 2006 Oct; 11(3-4):249-68.
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