 Receptors, Adrenergic, alpha
"Receptors, Adrenergic, alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major pharmacological subdivisions of adrenergic receptors that were originally defined by the relative potencies of various adrenergic compounds. The alpha receptors were initially described as excitatory receptors that post-junctionally stimulate SMOOTH MUSCLE contraction. However, further analysis has revealed a more complex picture involving several alpha receptor subtypes and their involvement in feedback regulation.
| Descriptor ID |
D011942
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| MeSH Number(s) |
D12.776.543.750.670.300.300.300 D12.776.543.750.695.150.300.300 D12.776.543.750.720.330.300.300
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| Concept/Terms |
Receptors, Adrenergic, alpha- Receptors, Adrenergic, alpha
- Adrenergic alpha-Receptors
- Adrenergic alpha Receptors
- alpha-Receptors, Adrenergic
- alpha-Adrenergic Receptors
- alpha Adrenergic Receptors
- Receptor, Adrenergic, alpha
- Receptors, alpha-Adrenergic
- Receptors, alpha Adrenergic
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Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, alpha".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Adrenergic [D12.776.543.750.670.300.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.670.300.300.300]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Adrenergic [D12.776.543.750.695.150.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.695.150.300.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.720.330.300.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, alpha".
This graph shows the total number of publications written about "Receptors, Adrenergic, alpha" by people in this website by year, and whether "Receptors, Adrenergic, alpha" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 2 | 0 | 2 | | 2000 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Adrenergic, alpha" by people in Profiles.
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Hashimoto R, Lanier GM, Dhagia V, Joshi SR, Jordan A, Waddell I, Tuder R, Stenmark KR, Wolin MS, McMurtry IF, Gupte SA. Pluripotent hematopoietic stem cells augment a-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2020 02 01; 318(2):L386-L401.
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Hammond KP, Nielsen C, Linnebur SA, Langness JA, Ray G, Maroni P, Kiser JJ. Priapism induced by boceprevir-CYP3A4 inhibition and a-adrenergic blockade: case report. Clin Infect Dis. 2014 Jan; 58(1):e35-8.
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Murphy GA, Fiuzat M, Bristow MR. Targeting heart failure therapeutics: a historical perspective. Heart Fail Clin. 2010 Jan; 6(1):11-23.
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Gosain A, Muthu K, Gamelli RL, DiPietro LA. Norepinephrine suppresses wound macrophage phagocytic efficiency through alpha- and beta-adrenoreceptor dependent pathways. Surgery. 2007 Aug; 142(2):170-9.
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Johnson JD, Fleshner M. Releasing signals, secretory pathways, and immune function of endogenous extracellular heat shock protein 72. J Leukoc Biol. 2006 Mar; 79(3):425-34.
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Montgomery DE, Wolska BM, Pyle WG, Roman BB, Dowell JC, Buttrick PM, Koretsky AP, Del Nido P, Solaro RJ. alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI. Am J Physiol Heart Circ Physiol. 2002 Jun; 282(6):H2397-405.
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Pulido EJ, Shames BD, Fullerton DA, Sheridan BC, Selzman CH, Gamboni-Robertson F, Bensard DD, McIntyre RC. Differential inducible nitric oxide synthase expression in systemic and pulmonary vessels after endotoxin. Am J Physiol Regul Integr Comp Physiol. 2000 May; 278(5):R1232-9.
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Snell LD, Claffey DJ, Ruth JA, Valenzuela CF, Cardoso R, Wang Z, Levinson SR, Sather WA, Williamson AV, Ingersoll NC, Ovchinnikova L, Bhave SV, Hoffman PL, Tabakoff B. Novel structure having antagonist actions at both the glycine site of the N-methyl-D-aspartate receptor and neuronal voltage-sensitive sodium channels: biochemical, electrophysiological, and behavioral characterization. J Pharmacol Exp Ther. 2000 Jan; 292(1):215-27.
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Palmer BM, Olsson MC, Lynch JM, Mace LC, Snyder SM, Valent S, Moore RL. Chronic run training suppresses alpha-adrenergic response of rat cardiomyocytes and isovolumic left ventricle. Am J Physiol. 1999 12; 277(6):H2136-44.
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Cleveland JC, Meldrum DR, Rowland RT, Cain BS, Meng X, Gamboni-Robertson F, Banerjee A, Harken AH. Ischemic preconditioning of human myocardium: protein kinase C mediates a permissive role for alpha 1-adrenoceptors. Am J Physiol. 1997 Aug; 273(2 Pt 2):H902-8.
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