Receptors, Adrenergic, alpha-2
"Receptors, Adrenergic, alpha-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of alpha-adrenergic receptors found on both presynaptic and postsynaptic membranes where they signal through Gi-Go G-PROTEINS. While postsynaptic alpha-2 receptors play a traditional role in mediating the effects of ADRENERGIC AGONISTS, the subset of alpha-2 receptors found on presynaptic membranes signal the feedback inhibition of NEUROTRANSMITTER release.
Descriptor ID |
D018341
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MeSH Number(s) |
D12.776.543.750.670.300.300.300.200 D12.776.543.750.695.150.300.300.725 D12.776.543.750.720.330.300.300.200
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Concept/Terms |
Receptors, Adrenergic, alpha-2- Receptors, Adrenergic, alpha-2
- alpha 2 Adrenergic Receptors
- Receptor, Adrenergic, alpha-2
- Adrenergic alpha-2 Receptors
- Adrenergic alpha 2 Receptors
- Receptors, Adrenergic alpha-2
- alpha-2 Receptors, Adrenergic
- Receptors, alpha-2 Adrenergic
- Receptors, alpha 2 Adrenergic
- Adrenergic Receptor, alpha-2
- Adrenergic Receptor, alpha 2
- Receptor, alpha-2 Adrenergic
- alpha-2 Adrenergic Receptor
- alpha-2 Adrenergic Receptors
- Adrenergic Receptors, alpha-2
Receptor, Adrenergic, alpha-2D- Receptor, Adrenergic, alpha-2D
- Adrenergic Receptor alpha(2d)
- Receptors, Adrenergic, alpha-2D
- Adrenergic alpha-2D Receptors
- Adrenergic alpha 2D Receptors
- Receptors, Adrenergic alpha-2D
- alpha-2D Receptors, Adrenergic
- alpha-2D Adrenergic Receptor
- Adrenergic Receptor, alpha-2D
- Receptor, alpha-2D Adrenergic
- alpha 2D Adrenergic Receptor
Receptor, Adrenergic, alpha-2C- Receptor, Adrenergic, alpha-2C
- Adrenergic Receptor alpha-2C
- Adrenergic Receptor alpha 2C
- Receptor alpha-2C, Adrenergic
- alpha-2C, Adrenergic Receptor
- alpha-2C Adrenergic Receptor
- Adrenergic Receptor, alpha-2C
- Receptor, alpha-2C Adrenergic
- alpha 2C Adrenergic Receptor
- Adrenergic Receptor alpha(2C)
- Adrenergic alpha-2C Receptors
- Adrenergic alpha 2C Receptors
- Receptors, Adrenergic alpha-2C
- alpha-2C Receptors, Adrenergic
Receptor, Adrenergic, alpha-2A- Receptor, Adrenergic, alpha-2A
- alpha-2A Adrenergic Receptor
- Adrenergic Receptor, alpha-2A
- Receptor, alpha-2A Adrenergic
- alpha 2A Adrenergic Receptor
- Receptors, Adrenergic, alpha-2A
- Adrenergic alpha-2A Receptors
- Adrenergic alpha 2A Receptors
- Receptors, Adrenergic alpha-2A
- alpha-2A Receptors, Adrenergic
Receptor, Adrenergic, alpha-2B- Receptor, Adrenergic, alpha-2B
- Adrenergic Receptor alpha-2b
- Adrenergic Receptor alpha 2b
- Receptor alpha-2b, Adrenergic
- alpha-2b, Adrenergic Receptor
- Receptors, Adrenergic, alpha-2B
- Adrenergic alpha-2B Receptors
- Adrenergic alpha 2B Receptors
- Receptors, Adrenergic alpha-2B
- alpha-2B Receptors, Adrenergic
- alpha-2B Adrenergic Receptor
- Adrenergic Receptor, alpha-2B
- Receptor, alpha-2B Adrenergic
- alpha 2B Adrenergic Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, alpha-2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Adrenergic [D12.776.543.750.670.300.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.670.300.300.300]
- Receptors, Adrenergic, alpha-2 [D12.776.543.750.670.300.300.300.200]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Adrenergic [D12.776.543.750.695.150.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.695.150.300.300]
- Receptors, Adrenergic, alpha-2 [D12.776.543.750.695.150.300.300.725]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.720.330.300.300]
- Receptors, Adrenergic, alpha-2 [D12.776.543.750.720.330.300.300.200]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, alpha-2".
This graph shows the total number of publications written about "Receptors, Adrenergic, alpha-2" by people in this website by year, and whether "Receptors, Adrenergic, alpha-2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 | 2009 | 1 | 0 | 1 | 2012 | 2 | 0 | 2 | 2013 | 2 | 0 | 2 | 2014 | 1 | 0 | 1 | 2017 | 1 | 0 | 1 | 2018 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Adrenergic, alpha-2" by people in Profiles.
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Parikh KS, Fiuzat M, Davis G, Neely M, Blain-Nelson P, Whellan DJ, Abraham WT, Adams KF, Felker GM, Liggett SB, O'Connor CM, Bristow MR. Dose Response of ?-Blockers in Adrenergic Receptor Polymorphism Genotypes. Circ Genom Precis Med. 2018 08; 11(8):e002210.
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Jepma M, Brown SBRE, Murphy PR, Koelewijn SC, de Vries B, van den Maagdenberg AM, Nieuwenhuis S. Noradrenergic and Cholinergic Modulation of Belief Updating. J Cogn Neurosci. 2018 12; 30(12):1803-1820.
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Friesen RH, Slavov D, Miyamoto SD, John Ing R, LaRiviere WB, Taylor MRG. Lack of Association Between Adrenoreceptor Genotype and the Vasoconstriction Response to Dexmedetomidine. Semin Cardiothorac Vasc Anesth. 2017 Dec; 21(4):341-344.
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Vo L, Drummond PD. Effect of combined opioid receptor and a2-adrenoceptor blockade on anxiety and electrically evoked startle responses. J Psychopharmacol. 2017 06; 31(6):722-729.
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Vo L, Hood S, Drummond PD. Involvement of Opioid Receptors and a2-Adrenoceptors in Inhibitory Pain Modulation Processes: A Double-Blind Placebo-Controlled Crossover Study. J Pain. 2016 11; 17(11):1164-1173.
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Courtney NA, Ford CP. The timing of dopamine- and noradrenaline-mediated transmission reflects underlying differences in the extent of spillover and pooling. J Neurosci. 2014 May 28; 34(22):7645-56.
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Todd RM, M?ller DJ, Lee DH, Robertson A, Eaton T, Freeman N, Palombo DJ, Levine B, Anderson AK. Genes for emotion-enhanced remembering are linked to enhanced perceiving. Psychol Sci. 2013 Nov 01; 24(11):2244-53.
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Bell MT, Puskas F, Bennett DT, Herson PS, Quillinan N, Fullerton DA, Reece TB. Dexmedetomidine, an a-2a adrenergic agonist, promotes ischemic tolerance in a murine model of spinal cord ischemia-reperfusion. J Thorac Cardiovasc Surg. 2014 Jan; 147(1):500-6.
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Bell MT, Agoston VA, Freeman KA, Puskas F, Herson PS, Mares J, Fullerton DA, Reece TB. Interruption of spinal cord microglial signaling by alpha-2 agonist dexmedetomidine in a murine model of delayed paraplegia. J Vasc Surg. 2014 Apr; 59(4):1090-7.
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Aleong RG, Sauer WH, Robertson AD, Liggett SB, Bristow MR. Adrenergic receptor polymorphisms and prevention of ventricular arrhythmias with bucindolol in patients with chronic heart failure. Circ Arrhythm Electrophysiol. 2013 Feb; 6(1):137-43.
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