 Glucose Transporter Type 4
"Glucose Transporter Type 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glucose transport protein found in mature MUSCLE CELLS and ADIPOCYTES. It promotes transport of glucose from the BLOOD into target TISSUES. The inactive form of the protein is localized in CYTOPLASMIC VESICLES. In response to INSULIN, it is translocated to the PLASMA MEMBRANE where it facilitates glucose uptake.
| Descriptor ID |
D051275
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| MeSH Number(s) |
D12.776.157.530.500.500.937 D12.776.157.530.937.563.937 D12.776.543.585.500.500.937 D12.776.543.585.937.625.937
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| Concept/Terms |
Glucose Transporter Type 4- Glucose Transporter Type 4
- Insulin-Responsive Glucose Transporter
- Glucose Transporter, Insulin-Responsive
- Insulin Responsive Glucose Transporter
- SLC2A4 Protein
- Solute Carrier Family 2, Facilitated Glucose Transporter, Member 4 Protein
- GLUT4 Protein
- GLUT-4 Protein
- GLUT 4 Protein
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Below are MeSH descriptors whose meaning is more general than "Glucose Transporter Type 4".
Below are MeSH descriptors whose meaning is more specific than "Glucose Transporter Type 4".
This graph shows the total number of publications written about "Glucose Transporter Type 4" by people in this website by year, and whether "Glucose Transporter Type 4" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 1 | 3 | | 2013 | 1 | 2 | 3 | | 2014 | 0 | 3 | 3 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glucose Transporter Type 4" by people in Profiles.
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Perreault L, Skyler JS, Rosenstock J. Novel therapies with precision mechanisms for type 2 diabetes mellitus. Nat Rev Endocrinol. 2021 06; 17(6):364-377.
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Wang S, Liu Y, Crisman L, Wan C, Miller J, Yu H, Shen J. Genetic evidence for an inhibitory role of tomosyn in insulin-stimulated GLUT4 exocytosis. Traffic. 2020 10; 21(10):636-646.
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Wang S, Crisman L, Miller J, Datta I, Gulbranson DR, Tian Y, Yin Q, Yu H, Shen J. Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis. J Biol Chem. 2019 Dec 27; 294(52):19988-19996.
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Yu H, Crisman L, Stowell MHB, Shen J. Functional Reconstitution of Intracellular Vesicle Fusion Using Purified SNAREs and Sec1/Munc18 (SM) Proteins. Methods Mol Biol. 2019; 1860:237-249.
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Stierwalt HD, Ehrlicher SE, Bergman BC, Robinson MM, Newsom SA. Insulin-stimulated Rac1-GTP binding is not impaired by palmitate treatment in L6 myotubes. Physiol Rep. 2018 Dec; 6(24):e13956.
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Guan X, Chaffey PK, Wei X, Gulbranson DR, Ruan Y, Wang X, Li Y, Ouyang Y, Chen L, Zeng C, Koelsch TN, Tran AH, Liang W, Shen J, Tan Z. Chemically Precise Glycoengineering Improves Human Insulin. ACS Chem Biol. 2018 01 19; 13(1):73-81.
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Gulbranson DR, Davis EM, Demmitt BA, Ouyang Y, Ye Y, Yu H, Shen J. RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis. Proc Natl Acad Sci U S A. 2017 09 26; 114(39):E8224-E8233.
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Ruebel M, Shankar K, Gaddy D, Lindsey F, Badger T, Andres A. Maternal obesity is associated with ovarian inflammation and upregulation of early growth response factor 1. Am J Physiol Endocrinol Metab. 2016 07 01; 311(1):E269-77.
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Bruns DR, Brown RD, Stenmark KR, Buttrick PM, Walker LA. Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction. Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15; 308(2):L158-67.
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Yu H, Rathore SS, Gulbranson DR, Shen J. The N- and C-terminal domains of tomosyn play distinct roles in soluble N-ethylmaleimide-sensitive factor attachment protein receptor binding and fusion regulation. J Biol Chem. 2014 Sep 12; 289(37):25571-80.
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