 Diphenhydramine
"Diphenhydramine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
| Descriptor ID |
D004155
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| MeSH Number(s) |
D02.092.471.320 D02.455.426.559.389.115.250
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| Concept/Terms |
Diphenhydramine- Diphenhydramine
- Benzhydramine
- Diphenylhydramine
- Diphenylhydramin
- 2-Diphenylmethoxy-N,N-dimethylethylamine
- Benhydramin
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Below are MeSH descriptors whose meaning is more general than "Diphenhydramine".
Below are MeSH descriptors whose meaning is more specific than "Diphenhydramine".
This graph shows the total number of publications written about "Diphenhydramine" by people in this website by year, and whether "Diphenhydramine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2015 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 0 | 2 | 2 | | 2021 | 0 | 1 | 1 | | 2022 | 0 | 2 | 2 | | 2023 | 1 | 2 | 3 |
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Below are the most recent publications written about "Diphenhydramine" by people in Profiles.
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Mariotti AL, Pattee J, Edmundowicz SA, Hardesty TD, Sharma SM, Lemley MG, Rist SD, Weitzel N, Faruki AA. Operational outcomes of propofol sedation versus fentanyl, midazolam and diphenhydramine sedation for endoscopies and colonoscopies at an academic medical center. PLoS One. 2023; 18(11):e0294418.
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Mehrpour O, Hoyte C, Al Masud A, Biswas A, Schimmel J, Nakhaee S, Nasr MS, Delva-Clark H, Goss F. Deep learning neural network derivation and testing to distinguish acute poisonings. Expert Opin Drug Metab Toxicol. 2023 Jan-Jun; 19(6):367-380.
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Simon M, Heard K. Are antimuscarinic effects common in hydroxyzine overdose? A cohort analysis of antimuscarinic effects in hydroxyzine and diphenhydramine-poisoned patients. Clin Toxicol (Phila). 2023 05; 61(5):379-386.
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Mehrpour O, Hoyte C, Delva-Clark H, Al Masud A, Biswas A, Schimmel J, Nakhaee S, Goss F. Classification of acute poisoning exposures with machine learning models derived from the National Poison Data System. Basic Clin Pharmacol Toxicol. 2022 Dec; 131(6):566-574.
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Wang GS, Reynolds KM, Banner W, Bond GR, Kauffman RE, Palmer RB, Paul IM, Rapp-Olsson M, Green JL, Dart RC. Adverse Events Related to Accidental Unintentional Ingestions From Cough and Cold Medications in Children. Pediatr Emerg Care. 2022 Jan 01; 38(1):e100-e104.
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Halmo LS, Wang GS, Reynolds KM, Delva-Clark H, Rapp-Olsson M, Banner W, Bond GR, Kauffman RE, Palmer RB, Paul IM, Green JL, Dart RC. Pediatric Fatalities Associated With Over-the-Counter Cough and Cold Medications. Pediatrics. 2021 11; 148(5).
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Wang GS, Baker K, Ng P, Janis GC, Leonard J, Mistry RD, Heard K. A randomized trial comparing physostigmine vs lorazepam for treatment of antimuscarinic (anticholinergic) toxidrome. Clin Toxicol (Phila). 2021 Aug; 59(8):698-704.
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Wang GS, Green JL, Reynolds KM, Banner W, Bond GR, Kauffman RE, Palmer RB, Paul IM, Rapp-Olsson M, Dart RC. Trends in adverse events and related health-care facility utilization from cough and cold medication exposures in children. Clin Toxicol (Phila). 2021 Apr; 59(4):351-354.
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Wang GS, Reynolds KM, Banner W, Bond GR, Kauffman RE, Palmer RB, Paul IM, Rapp-Olsson M, Green JL, Dart RC. Medication Errors From Over-the-Counter Cough and Cold Medications in Children. Acad Pediatr. 2020 04; 20(3):327-332.
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Ngo SY, Rabbat JC. Systemic IgE-mediated hypersensitivity reaction to topical polymyxin B. J Allergy Clin Immunol Pract. 2019 Feb; 7(2):734-735.
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