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Santos J. Franco

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

    Collapse Biography 
    Collapse education and training
    Colorado State University, Fort Collins, COB.S.05/2000Biological Sciences
    University of Wisconsin, Madison, WIPh.D.08/2005Cellular and Molecular Biology
    The Scripps Research Institute, La Jolla, CAPostdoctoral07/2013Developmental Neuroscience

    Collapse Research 
    Collapse research activities and funding
    F32NS060355     (FRANCO, SANTOS JOE)Aug 1, 2009 - Jul 31, 2012
    Mechanisms of Reelin Action on neuronal Migration During Neocortical Lamination
    Role: Principal Investigator

    R56NS109239     (FRANCO, SANTOS JOE)Dec 15, 2018 - Nov 30, 2019
    Mechanisms of Oligodendrocyte Fate Specification in the Developing Neocortex
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Fregoso SP, Dwyer BE, Franco SJ. Lmx1a drives Cux2 expression in the cortical hem through activation of a conserved intronic enhancer. Development. 2019 Mar 07; 146(5). PMID: 30770393.
      View in: PubMed
    2. Winkler CC, Yabut OR, Fregoso SP, Gomez HG, Dwyer BE, Pleasure SJ, Franco SJ. The Dorsal Wave of Neocortical Oligodendrogenesis Begins Embryonically and Requires Multiple Sources of Sonic Hedgehog. J Neurosci. 2018 Jun 06; 38(23):5237-5250. PMID: 29739868.
      View in: PubMed
    3. Kazmierczak M, Kazmierczak P, Peng AW, Harris SL, Shah P, Puel JL, Lenoir M, Franco SJ, Schwander M. Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner. J Neurosci. 2017 03 29; 37(13):3447-3464. PMID: 28209736.
      View in: PubMed
    4. Martinez-Garay I, Gil-Sanz C, Franco SJ, Espinosa A, Molnár Z, Mueller U. Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development. 2016 06 15; 143(12):2121-34. PMID: 27151949; PMCID: PMC4920171.
    5. Gil-Sanz C, Espinosa A, Fregoso SP, Bluske KK, Cunningham CL, Martinez-Garay I, Zeng H, Franco SJ, Müller U. Lineage Tracing Using Cux2-Cre and Cux2-CreERT2 Mice. Neuron. 2015 May 20; 86(4):1091-1099. PMID: 25996136; PMCID: PMC4455040.
    6. Trotter J, Lee GH, Kazdoba TM, Crowell B, Domogauer J, Mahoney HM, Franco SJ, Müller U, Weeber EJ, D'Arcangelo G. Dab1 is required for synaptic plasticity and associative learning. J Neurosci. 2013 Sep 25; 33(39):15652-68. PMID: 24068831; PMCID: PMC3782631.
    7. Gil-Sanz C, Franco SJ, Martinez-Garay I, Espinosa A, Harkins-Perry S, Müller U. Cajal-Retzius cells instruct neuronal migration by coincidence signaling between secreted and contact-dependent guidance cues. Neuron. 2013 Aug 07; 79(3):461-77. PMID: 23931996; PMCID: PMC3774067.
    8. Brunne B, Franco S, Bouché E, Herz J, Howell BW, Pahle J, Müller U, May P, Frotscher M, Bock HH. Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by Reelin signaling mutant mice. Glia. 2013 Aug; 61(8):1347-63. PMID: 23828756; PMCID: PMC4065866.
    9. Franco SJ, Müller U. Shaping our minds: stem and progenitor cell diversity in the mammalian neocortex. Neuron. 2013 Jan 09; 77(1):19-34. PMID: 23312513; PMCID: PMC3557841.
    10. Franco SJ, Gil-Sanz C, Martinez-Garay I, Espinosa A, Harkins-Perry SR, Ramos C, Müller U. Fate-restricted neural progenitors in the mammalian cerebral cortex. Science. 2012 Aug 10; 337(6095):746-9. PMID: 22879516; PMCID: PMC4287277.
    11. Franco SJ, Müller U. Extracellular matrix functions during neuronal migration and lamination in the mammalian central nervous system. Dev Neurobiol. 2011 Nov; 71(11):889-900. PMID: 21739613.
      View in: PubMed
    12. Franco SJ, Martinez-Garay I, Gil-Sanz C, Harkins-Perry SR, Müller U. Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex. Neuron. 2011 Feb 10; 69(3):482-97. PMID: 21315259; PMCID: PMC3056352.
    13. Barros CS, Franco SJ, Müller U. Extracellular matrix: functions in the nervous system. Cold Spring Harb Perspect Biol. 2011 Jan 01; 3(1):a005108. PMID: 21123393; PMCID: PMC3003458.
    14. Simonson WT, Franco SJ, Huttenlocher A. Talin1 regulates TCR-mediated LFA-1 function. J Immunol. 2006 Dec 01; 177(11):7707-14. PMID: 17114441.
      View in: PubMed
    15. Franco SJ, Senetar MA, Simonson WT, Huttenlocher A, McCann RO. The conserved C-terminal I/LWEQ module targets Talin1 to focal adhesions. Cell Motil Cytoskeleton. 2006 Sep; 63(9):563-81. PMID: 16830345.
      View in: PubMed
    16. Franco SJ, Huttenlocher A. Regulating cell migration: calpains make the cut. J Cell Sci. 2005 Sep 01; 118(Pt 17):3829-38. PMID: 16129881.
      View in: PubMed
    17. Franco SJ, Rodgers MA, Perrin BJ, Han J, Bennin DA, Critchley DR, Huttenlocher A. Calpain-mediated proteolysis of talin regulates adhesion dynamics. Nat Cell Biol. 2004 Oct; 6(10):977-83. PMID: 15448700.
      View in: PubMed
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