Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Liyen Loh

TitleAssistant Research Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-IMM MICRO GENERAL OPER
Phone303/724-4224

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Park H, Choe J, Lee SM, Lim S, Lee JS, Oh YM, Lee JB, Hwang HJ, Yun J, Bae S, Yu D, Loh LC, Ong CK, Seo JB. Bronchiectasis in patients with chronic obstructive pulmonary disease: AI-based CT quantification using the bronchial tapering ratio. Eur Radiol. 2025 Aug 26. PMID: 40858775.
      View in: PubMed
    2. Knox-Brown B, Potts J, Franssen FME, Nielsen R, Denguezli M, Rotevatn AØ, Juvekar SK, Cherkaski HH, Studnicka M, Sylvester KP, Mortimer K, Bateman ED, Janson C, Malinovschi A, Seemungal T, Koul P, Mannino D, Mahesh PA, Jogi R, Mejza F, Al Ghobain M, Paraguas SNM, Welte T, Wouters E, Gislason T, Harrabi I, Dias H, Obaseki DO, Kocabas A, Barbara C, Cardoso J, Agarwal D, Nafees AA, Rodrigues F, Garcia-Larsen V, Erhabor GE, Loh LC, Amaral AFS. Concordance between FVC and FEV6 for identifying chronic airflow obstruction and spirometric restriction in the Burden of Obstructive Lung Disease (BOLD) study. BMJ Open Respir Res. 2025 Jul 13; 12(1). PMID: 40659415.
      View in: PubMed
    3. Loh L, Orlicky DJ, Spengler A, Domenico J, Klarquist J, Levens C, Celli S, Kofonow JM, Robertson CE, Lantz O, Legoux F, Frank DN, Matsuda J, Norman PJ, Kuhn KA, Onyiah J, Gapin L. MAIT cells exacerbate colonic inflammation in a genetically diverse murine model of spontaneous colitis. Mucosal Immunol. 2025 May 25. PMID: 40425090.
      View in: PubMed
    4. Knox-Brown B, Algharbi F, Mulhern O, Potts J, Harrabi I, Janson C, Nielsen R, Agarwal D, Malinovschi A, Juvekar S, Denguezli M, Gíslason T, Ahmed R, Nafees A, Koul PA, Obaseki D, Anand MP, Loh LC, Dias HB, Rodrigues F, Mannino D, Elbiaze M, El Rhazi K, Mejza F, Devereux G, Franssen FME, El Sony A, Wouters E, Al Ghobain M, Mortimer K, Rashid A, Osman R, Studnicka M, Cardoso J, Burney P, Amaral AFS. Bronchodilator responsiveness and future chronic airflow obstruction: a multinational longitudinal study. EClinicalMedicine. 2025 Mar; 81:103123. PMID: 40083442.
      View in: PubMed
    5. Rødahl IE, Ivarsson MA, Loh L, Mold JE, Westgren M, Friberg D, Mjösberg J, Björkström NK, Marquardt N, Nixon DF, Michaëlsson J. Distinct Tissue-Dependent Composition and Gene Expression of Human Fetal Innate Lymphoid Cells. Eur J Immunol. 2025 Feb; 55(2):e202451150. PMID: 39676343.
      View in: PubMed
    6. Loh L, Saunders PM, Faoro C, Font-Porterias N, Nemat-Gorgani N, Harrison GF, Sadeeq S, Hensen L, Wong SC, Widjaja J, Clemens EB, Zhu S, Kichula KM, Tao S, Zhu F, Montero-Martin G, Fernandez-Vina M, Guethlein LA, Vivian JP, Davies J, Mentzer AJ, Oppenheimer SJ, Pomat W, Ioannidis AG, Barberena-Jonas C, Moreno-Estrada A, Miller A, Parham P, Rossjohn J, Tong SYC, Kedzierska K, Brooks AG, Norman PJ. An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania. Cell. 2024 Nov 27; 187(24):7008-7024.e19. PMID: 39476840.
      View in: PubMed
    7. Loh L, Carcy S, Krovi HS, Domenico J, Spengler A, Lin Y, Torres J, Prabakar RK, Palmer W, Norman PJ, Stone M, Brunetti T, Meyer HV, Gapin L. Unraveling the phenotypic states of human innate-like T?cells: Comparative insights with conventional T?cells and mouse models. Cell Rep. 2024 09 24; 43(9):114705. PMID: 39264810.
      View in: PubMed
    8. Jia X, Crawford JC, Gebregzabher D, Monson EA, Mettelman RC, Wan Y, Ren Y, Chou J, Novak T, McQuilten HA, Clarke M, Bachem A, Foo IJ, Fritzlar S, Carrera Montoya J, Trenerry AM, Nie S, Leeming MG, Nguyen THO, Kedzierski L, Littler DR, Kueh A, Cardamone T, Wong CY, Hensen L, Cabug A, Laguna JG, Agrawal M, Flerlage T, Boyd DF, Van de Velde LA, Habel JR, Loh L, Koay HF, van de Sandt CE, Konstantinov IE, Berzins SP, Flanagan KL, Wakim LM, Herold MJ, Green AM, Smallwood HS, Rossjohn J, Thwaites RS, Chiu C, Scott NE, Mackenzie JM, Bedoui S, Reading PC, Londrigan SL, Helbig KJ, Randolph AG, Thomas PG, Xu J, Wang Z, Chua BY, Kedzierska K. High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases. Cell. 2024 Aug 22; 187(17):4586-4604.e20. PMID: 39137778.
      View in: PubMed
    9. Tobin R, Katsnelson EN, Couts KL, Spengler A, Loh L, Gapin L, McCarter MD. YIA24-005: MAIT Cells are Reduced in Anorectal Mucosal Melanomas Compared to Cutaneous Melanoma GI Metastases. J Natl Compr Canc Netw. 2024 Apr 05; 22(2.5). PMID: 38579822.
      View in: PubMed
    10. Abozid H, Patel J, Burney P, Hartl S, Breyer-Kohansal R, Mortimer K, Nafees AA, Al Ghobain M, Welte T, Harrabi I, Denguezli M, Loh LC, Rashid A, Gislason T, Barbara C, Cardoso J, Rodrigues F, Seemungal T, Obaseki D, Juvekar S, Paraguas SN, Tan WC, Franssen FME, Mejza F, Mannino D, Janson C, Cherkaski HH, Anand MP, Hafizi H, Buist S, Koul PA, El Sony A, Breyer MK, Burghuber OC, Wouters EFM, Amaral AFS. Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study. EClinicalMedicine. 2024 Feb; 68:102423. PMID: 38268532.
      View in: PubMed
    11. Katsnelson EN, Spengler A, Domenico J, Couts KL, Loh L, Gapin L, McCarter MD, Tobin RP. Dysfunctional states of unconventional T-cell subsets in cancer. J Leukoc Biol. 2024 01 05; 115(1):36-46. PMID: 37837379.
      View in: PubMed
    12. Amaral AFS, Potts J, Knox-Brown B, Bagkeris E, Harrabi I, Cherkaski HH, Agarwal D, Juvekar S, Anand MP, Gislason T, Nafees AA, Mortimer K, Janson C, Loh LC, Paraguas SN, Denguezli M, Al Ghobain M, Mannino D, Njoroge MW, Devereux G, Seemungal T, Barbara C, Kocabas A, Ahmed R, Aquart-Stewart A, Studnicka M, Welte T, Tan WC, van Zyl-Smit RN, Koul P, Garcia-Larsen V, Minelli C, Buist AS, Burney P. Cohort Profile: Burden of Obstructive Lung Disease (BOLD) study. Int J Epidemiol. 2023 12 25; 52(6):e364-e373. PMID: 37862437.
      View in: PubMed
    13. Loh L, Carcy S, Krovi HS, Domenico J, Spengler A, Lin Y, Torres J, Palmer W, Norman PJ, Stone M, Brunetti T, Meyer HV, Gapin L. Unraveling the Phenotypic States of Human innate-like T Cells: Comparative Insights with Conventional T Cells and Mouse Models. bioRxiv. 2023 Dec 08. PMID: 38105962.
      View in: PubMed
    14. Loh L, Orlicky D, Spengler A, Levens C, Celli S, Domenico J, Klarquist J, Onyiah J, Matsuda J, Kuhn K, Gapin L. MAIT cells drive chronic inflammation in a genetically diverse murine model of spontaneous colitis. bioRxiv. 2023 Dec 01. PMID: 38076996.
      View in: PubMed
    15. Palmer WH, Leaton LA, Campos Codo A, Crute B, Roest J, Zhu S, Petersen J, Tobin RP, Hume PS, Stone M, van Bokhoven A, Gerich ME, McCarter MD, Zhu Y, Janssen WJ, Vivian JP, Trowsdale J, Getahun A, Rossjohn J, Cambier J, Loh L, Norman PJ. Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells. Sci Immunol. 2023 06 30; 8(84):eade5343. PMID: 37390222.
      View in: PubMed
    16. Knox-Brown B, Patel J, Potts J, Ahmed R, Aquart-Stewart A, Barbara C, Buist AS, Cherkaski HH, Denguezli M, Elbiaze M, Erhabor GE, Franssen FME, Al Ghobain M, Gislason T, Janson C, Kocabas A, Mannino D, Marks G, Mortimer K, Nafees AA, Obaseki D, Paraguas SNM, Loh LC, Rashid A, Salvi S, Seemungal T, Studnicka M, Tan WC, Wouters EFM, Abozid H, Mueller A, Burney P, Amaral AFS. The association of spirometric small airways obstruction with respiratory symptoms, cardiometabolic diseases, and quality of life: results from the Burden of Obstructive Lung Disease (BOLD) study. Respir Res. 2023 May 23; 24(1):137. PMID: 37221593.
      View in: PubMed
    17. Ratanachina J, Amaral AFS, De Matteis S, Lawin H, Mortimer K, Obaseki DO, Harrabi I, Denguezli M, Wouters EFM, Janson C, Nielsen R, Gulsvik A, Cherkaski HH, Mejza F, Mahesh PA, Elsony A, Ahmed R, Tan W, Loh LC, Rashid A, Studnicka M, Nafees AA, Seemungal T, Aquart-Stewart A, Al Ghobain M, Zheng J, Juvekar S, Salvi S, Jogi R, Mannino D, Gislason T, Buist AS, Cullinan P, Burney P. Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study. Eur Respir J. 2023 01; 61(1). PMID: 36028253.
      View in: PubMed
    18. Knox-Brown B, Patel J, Potts J, Ahmed R, Aquart-Stewart A, Cherkaski HH, Denguezli M, Elbiaze M, Elsony A, Franssen FME, Ghobain MA, Harrabi I, Janson C, Jõgi R, Juvekar S, Lawin H, Mannino D, Mortimer K, Nafees AA, Nielsen R, Obaseki D, Paraguas SNM, Rashid A, Loh LC, Salvi S, Seemungal T, Studnicka M, Tan WC, Wouters EEFM, Barbara C, Gislason T, Gunasekera K, Burney P, Amaral AFS. Small airways obstruction and its risk factors in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study. Lancet Glob Health. 2023 01; 11(1):e69-e82. PMID: 36521955.
      View in: PubMed
    19. Krovi SH, Loh L, Spengler A, Brunetti T, Gapin L. Current insights in mouse iNKT and MAIT cell development using single cell transcriptomics data. Semin Immunol. 2022 03; 60:101658. PMID: 36182863.
      View in: PubMed
    20. Habel JR, Nguyen AT, Rowntree LC, Szeto C, Mifsud NA, Clemens EB, Loh L, Chen W, Rockman S, Nelson J, Davies J, Miller A, Tong SYC, Rossjohn J, Gras S, Purcell AW, Hensen L, Kedzierska K, Illing PT. HLA-A*11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people. PLoS Pathog. 2022 03; 18(3):e1010337. PMID: 35255101.
      View in: PubMed
    21. Suliman S, Kjer-Nielsen L, Iwany SK, Lopez Tamara K, Loh L, Grzelak L, Kedzierska K, Ocampo TA, Corbett AJ, McCluskey J, Rossjohn J, Le?n SR, Calderon R, Lecca-Garcia L, Murray MB, Moody DB, Van Rhijn I. Dual TCR-a Expression on Mucosal-Associated Invariant T Cells as a Potential Confounder of TCR Interpretation. J Immunol. 2022 03 15; 208(6):1389-1395. PMID: 35246495.
      View in: PubMed
    22. Jia X, Chua BY, Loh L, Koutsakos M, Kedzierski L, Olshansky M, Heath WR, Chang SY, Xu J, Wang Z, Kedzierska K. High expression of CD38 and MHC class II on CD8+ T cells during severe influenza disease reflects bystander activation and trogocytosis. Clin Transl Immunology. 2021; 10(9):e1336. PMID: 34522380.
      View in: PubMed
    23. Burney P, Patel J, Minelli C, Gnatiuc L, Amaral AFS, Kocabas A, Cherkaski HH, Gulsvik A, Nielsen R, Bateman E, Jithoo A, Mortimer K, Sooronbaev TM, Lawin H, Nejjari C, Elbiaze M, El Rhazi K, Zheng JP, Ran P, Welte T, Obaseki D, Erhabor G, Elsony A, Osman NB, Ahmed R, Nizankowska-Mogilnicka E, Mejza F, Mannino DM, Bárbara C, Wouters EFM, Idolor LF, Loh LC, Rashid A, Juvekar S, Gislason T, Al Ghobain M, Studnicka M, Harrabi I, Denguezli M, Koul PA, Jenkins C, Marks G, Jõgi R, Hafizi H, Janson C, Tan WC, Aquart-Stewart A, Mbatchou B, Nafees AA, Gunasekera K, Seemungal T, Anand MP, Enright P, Vollmer WM, Blangiardo M, Elfadaly FG, Buist AS. Prevalence and Population-Attributable Risk for Chronic Airflow Obstruction in a Large Multinational Study. Am J Respir Crit Care Med. 2021 06 01; 203(11):1353-1365. PMID: 33171069.
      View in: PubMed
    24. Hensen L, Illing PT, Bridie Clemens E, Nguyen THO, Koutsakos M, van de Sandt CE, Mifsud NA, Nguyen AT, Szeto C, Chua BY, Halim H, Rizzetto S, Luciani F, Loh L, Grant EJ, Saunders PM, Brooks AG, Rockman S, Kotsimbos TC, Cheng AC, Richards M, Westall GP, Wakim LM, Loudovaris T, Mannering SI, Elliott M, Tangye SG, Jackson DC, Flanagan KL, Rossjohn J, Gras S, Davies J, Miller A, Tong SYC, Purcell AW, Kedzierska K. CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nat Commun. 2021 05 18; 12(1):2931. PMID: 34006841.
      View in: PubMed
    25. Nguyen THO, Koutsakos M, van de Sandt CE, Crawford JC, Loh L, Sant S, Grzelak L, Allen EK, Brahm T, Clemens EB, Auladell M, Hensen L, Wang Z, N?ssing S, Jia X, G?nther P, Wheatley AK, Kent SJ, Aban M, Deng YM, Laurie KL, Hurt AC, Gras S, Rossjohn J, Crowe J, Xu J, Jackson D, Brown LE, La Gruta N, Chen W, Doherty PC, Turner SJ, Kotsimbos TC, Thomas PG, Cheng AC, Kedzierska K. Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients. Nat Commun. 2021 05 11; 12(1):2691. PMID: 33976217.
      View in: PubMed
    26. Delpoux A, Marcel N, Hess Michelini R, Katayama CD, Allison KA, Glass CK, Qui?ones-Parra SM, Murre C, Loh L, Kedzierska K, Lappas M, Hedrick SM, Doedens AL. FOXO1 constrains activation and regulates senescence in CD8 T?cells. Cell Rep. 2021 01 26; 34(4):108674. PMID: 33503413.
      View in: PubMed
    27. Harsha Krovi S, Zhang J, Michaels-Foster MJ, Brunetti T, Loh L, Scott-Browne J, Gapin L. Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells. Nat Commun. 2020 12 07; 11(1):6238. PMID: 33288744.
      View in: PubMed
    28. Sant S, Qui?ones-Parra SM, Koutsakos M, Grant EJ, Loudovaris T, Mannering SI, Crowe J, van de Sandt CE, Rimmelzwaan GF, Rossjohn J, Gras S, Loh L, Nguyen THO, Kedzierska K. HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells. PLoS Pathog. 2020 08; 16(8):e1008714. PMID: 32750095.
      View in: PubMed
    29. Quinn KM, Hussain T, Kraus F, Formosa LE, Lam WK, Dagley MJ, Saunders EC, Assmus LM, Wynne-Jones E, Loh L, van de Sandt CE, Cooper L, Good-Jacobson KL, Kedzierska K, Mackay LK, McConville MJ, Ramm G, Ryan MT, La Gruta NL. Publisher Correction: Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality. Nat Commun. 2020 07 09; 11(1):3517. PMID: 32647122.
      View in: PubMed
    30. Quinn KM, Hussain T, Kraus F, Formosa LE, Lam WK, Dagley MJ, Saunders EC, Assmus LM, Wynne-Jones E, Loh L, van de Sandt CE, Cooper L, Good-Jacobson KL, Kedzierska K, Mackay LK, McConville MJ, Ramm G, Ryan MT, La Gruta NL. Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality. Nat Commun. 2020 06 05; 11(1):2857. PMID: 32504069.
      View in: PubMed
    31. Atkin-Smith GK, Duan M, Zanker DJ, Loh L, Nguyen THO, Koutsakos M, Nguyen T, Jiang X, Carrera J, Phan TK, Liu C, Paone S, Oveissi S, Hodge AL, Baxter AA, Kedzierska K, Mackenzie JM, Hulett MD, Bilsel P, Chen W, Poon IKH. Monocyte apoptotic bodies are vehicles for influenza A virus propagation. Commun Biol. 2020 05 08; 3(1):223. PMID: 32385344.
      View in: PubMed
    32. de Lima Moreira M, Souter MNT, Chen Z, Loh L, McCluskey J, Pellicci DG, Eckle SBG. Hypersensitivities following allergen antigen recognition by unconventional T cells. Allergy. 2020 10; 75(10):2477-2490. PMID: 32181878.
      View in: PubMed
    33. Tiew PY, Ko FWS, Narayana JK, Poh ME, Xu H, Neo HY, Loh LC, Ong CK, Mac Aogáin M, Tan JHY, Kamaruddin NH, Sim GJH, Lapperre TS, Koh MS, Hui DSC, Abisheganaden JA, Tee A, Tsaneva-Atanasova K, Chotirmall SH. "High-Risk" Clinical and Inflammatory Clusters in COPD of Chinese Descent. Chest. 2020 07; 158(1):145-156. PMID: 32092320.
      View in: PubMed
    34. Loh L, Gherardin NA, Sant S, Grzelak L, Crawford JC, Bird NL, Koay HF, van de Sandt CE, Moreira ML, Lappas M, Allen EK, Crowe J, Loudovaris T, Flanagan KL, Quinn KM, Rossjohn J, Thomas PG, Eckle SBG, McCluskey J, Godfrey DI, Kedzierska K. Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRa? Clonotypes with Potent Antimicrobial Responses. J Immunol. 2020 03 01; 204(5):1119-1133. PMID: 31988181.
      View in: PubMed
    35. Loh L, Koutsakos M, Kedzierska K, Hinks TSC. Influenza A Virus-Infected Lung Epithelial Cell Co-Culture with Human Peripheral Blood Mononuclear Cells. Methods Mol Biol. 2020; 2098:141-147. PMID: 31792820.
      View in: PubMed
    36. Hinks TSC, van Wilgenburg B, Wang H, Loh L, Koutsakos M, Kedzierska K, Corbett AJ, Chen Z. Study of MAIT Cell Activation in Viral Infections In Vivo. Methods Mol Biol. 2020; 2098:261-281. PMID: 31792828.
      View in: PubMed
    37. Souter MNT, Loh L, Li S, Meehan BS, Gherardin NA, Godfrey DI, Rossjohn J, Fairlie DP, Kedzierska K, Pellicci DG, Chen Z, Kjer-Nielsen L, Corbett AJ, McCluskey J, Eckle SBG. Characterization of Human Mucosal-associated Invariant T (MAIT) Cells. Curr Protoc Immunol. 2019 12; 127(1):e90. PMID: 31763790.
      View in: PubMed
    38. Sant S, Jenkins MR, Dash P, Watson KA, Wang Z, Pizzolla A, Koutsakos M, Nguyen TH, Lappas M, Crowe J, Loudovaris T, Mannering SI, Westall GP, Kotsimbos TC, Cheng AC, Wakim L, Doherty PC, Thomas PG, Loh L, Kedzierska K. Human ?d T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation. Clin Transl Immunology. 2019; 8(9):e1079. PMID: 31559018.
      View in: PubMed
    39. Yurick D, Khoury G, Clemens B, Loh L, Pham H, Kedzierska K, Einsiedel L, Purcell D. Multiplex Droplet Digital PCR Assay for Quantification of Human T-Cell Leukemia Virus Type 1 Subtype c DNA Proviral Load and T Cells from Blood and Respiratory Exudates Sampled in a Remote Setting. J Clin Microbiol. 2019 02; 57(2). PMID: 30518541.
      View in: PubMed
    40. Grant EJ, Josephs TM, Loh L, Clemens EB, Sant S, Bharadwaj M, Chen W, Rossjohn J, Gras S, Kedzierska K. Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans. Nat Commun. 2018 12 21; 9(1):5427. PMID: 30575715.
      View in: PubMed
    41. Dias J, Boulouis C, Gorin JB, van den Biggelaar RHGA, Lal KG, Gibbs A, Loh L, Gulam MY, Sia WR, Bari S, Hwang WYK, Nixon DF, Nguyen S, Betts MR, Buggert M, Eller MA, Broliden K, Tjernlund A, Sandberg JK, Leeansyah E. The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool. Proc Natl Acad Sci U S A. 2018 12 04; 115(49):E11513-E11522. PMID: 30442667.
      View in: PubMed
    42. van Wilgenburg B, Loh L, Chen Z, Pediongco TJ, Wang H, Shi M, Zhao Z, Koutsakos M, N?ssing S, Sant S, Wang Z, D'Souza C, Jia X, Almeida CF, Kostenko L, Eckle SBG, Meehan BS, Kallies A, Godfrey DI, Reading PC, Corbett AJ, McCluskey J, Klenerman P, Kedzierska K, Hinks TSC. MAIT cells contribute to protection against lethal influenza infection in vivo. Nat Commun. 2018 11 09; 9(1):4706. PMID: 30413689.
      View in: PubMed
    43. Sant S, Grzelak L, Wang Z, Pizzolla A, Koutsakos M, Crowe J, Loudovaris T, Mannering SI, Westall GP, Wakim LM, Rossjohn J, Gras S, Richards M, Xu J, Thomas PG, Loh L, Nguyen THO, Kedzierska K. Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection. Front Immunol. 2018; 9:1453. PMID: 29997621.
      View in: PubMed
    44. Quinn KM, Fox A, Harland KL, Russ BE, Li J, Nguyen THO, Loh L, Olshanksy M, Naeem H, Tsyganov K, Wiede F, Webster R, Blyth C, Sng XYX, Tiganis T, Powell D, Doherty PC, Turner SJ, Kedzierska K, La Gruta NL. Age-Related Decline in Primary CD8+ T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8+ T Cells. Cell Rep. 2018 06 19; 23(12):3512-3524. PMID: 29924995.
      View in: PubMed
    45. Gherardin NA, Loh L, Admojo L, Davenport AJ, Richardson K, Rogers A, Darcy PK, Jenkins MR, Prince HM, Harrison SJ, Quach H, Fairlie DP, Kedzierska K, McCluskey J, Uldrich AP, Neeson PJ, Ritchie DS, Godfrey DI. Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma. Sci Rep. 2018 03 07; 8(1):4159. PMID: 29515123.
      View in: PubMed
    46. Wang Z, Zhu L, Nguyen THO, Wan Y, Sant S, Qui?ones-Parra SM, Crawford JC, Eltahla AA, Rizzetto S, Bull RA, Qiu C, Koutsakos M, Clemens EB, Loh L, Chen T, Liu L, Cao P, Ren Y, Kedzierski L, Kotsimbos T, McCaw JM, La Gruta NL, Turner SJ, Cheng AC, Luciani F, Zhang X, Doherty PC, Thomas PG, Xu J, Kedzierska K. Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease. Nat Commun. 2018 02 26; 9(1):824. PMID: 29483513.
      View in: PubMed
    47. Koutsakos M, Wheatley AK, Loh L, Clemens EB, Sant S, N?ssing S, Fox A, Chung AW, Laurie KL, Hurt AC, Rockman S, Lappas M, Loudovaris T, Mannering SI, Westall GP, Elliot M, Tangye SG, Wakim LM, Kent SJ, Nguyen THO, Kedzierska K. Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity. Sci Transl Med. 2018 02 14; 10(428). PMID: 29444980.
      View in: PubMed
    48. Nguyen THO, Sant S, Bird NL, Grant EJ, Clemens EB, Koutsakos M, Valkenburg SA, Gras S, Lappas M, Jaworowski A, Crowe J, Loh L, Kedzierska K. Perturbed CD8+ T cell immunity across universal influenza epitopes in the elderly. J Leukoc Biol. 2018 02; 103(2):321-339. PMID: 28928269.
      View in: PubMed
    49. Amaral AFS, Patel J, Kato BS, Obaseki DO, Lawin H, Tan WC, Juvekar SK, Harrabi I, Studnicka M, Wouters EFM, Loh LC, Bateman ED, Mortimer K, Buist AS, Burney PGJ. Airflow Obstruction and Use of Solid Fuels for Cooking or Heating: BOLD Results. Am J Respir Crit Care Med. 2018 03 01; 197(5):595-610. PMID: 28895752.
      View in: PubMed
    50. Townend J, Minelli C, Mortimer K, Obaseki DO, Al Ghobain M, Cherkaski H, Denguezli M, Gunesekera K, Hafizi H, Koul PA, Loh LC, Nejjari C, Patel J, Sooronbayev T, Buist SA, Burney PGJ. The association between chronic airflow obstruction and poverty in 12 sites of the multinational BOLD study. Eur Respir J. 2017 06; 49(6). PMID: 28572124.
      View in: PubMed
    51. Koay HF, Gherardin NA, Enders A, Loh L, Mackay LK, Almeida CF, Russ BE, Nold-Petry CA, Nold MF, Bedoui S, Chen Z, Corbett AJ, Eckle SB, Meehan B, d'Udekem Y, Konstantinov IE, Lappas M, Liu L, Goodnow CC, Fairlie DP, Rossjohn J, Chong MM, Kedzierska K, Berzins SP, Belz GT, McCluskey J, Uldrich AP, Godfrey DI, Pellicci DG. A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage. Nat Immunol. 2016 Nov; 17(11):1300-1311. PMID: 27668799.
      View in: PubMed
    52. Loh L, Wang Z, Sant S, Koutsakos M, Jegaskanda S, Corbett AJ, Liu L, Fairlie DP, Crowe J, Rossjohn J, Xu J, Doherty PC, McCluskey J, Kedzierska K. Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation. Proc Natl Acad Sci U S A. 2016 09 06; 113(36):10133-8. PMID: 27543331.
      View in: PubMed
    53. Wang Z, Loh L, Kedzierski L, Kedzierska K. Avian Influenza Viruses, Inflammation, and CD8(+) T Cell Immunity. Front Immunol. 2016; 7:60. PMID: 26973644.
      View in: PubMed
    54. Wang Z, Wan Y, Qiu C, Qui?ones-Parra S, Zhu Z, Loh L, Tian D, Ren Y, Hu Y, Zhang X, Thomas PG, Inouye M, Doherty PC, Kedzierska K, Xu J. Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8? T cells. Nat Commun. 2015 May 13; 6:6833. PMID: 25967273.
      View in: PubMed
    55. Parsons MS, Loh L, Gooneratne S, Center RJ, Kent SJ. Role of education and differentiation in determining the potential of natural killer cells to respond to antibody-dependent stimulation. AIDS. 2014 Nov 28; 28(18):2781-6. PMID: 25493604.
      View in: PubMed
    56. Qui?ones-Parra S, Loh L, Brown LE, Kedzierska K, Valkenburg SA. Universal immunity to influenza must outwit immune evasion. Front Microbiol. 2014; 5:285. PMID: 24971078.
      View in: PubMed
    57. Jegaskanda S, Vandenberg K, Laurie KL, Loh L, Kramski M, Winnall WR, Kedzierska K, Rockman S, Kent SJ. Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity in intravenous immunoglobulin as a potential therapeutic against emerging influenza viruses. J Infect Dis. 2014 Dec 01; 210(11):1811-22. PMID: 24916185.
      View in: PubMed
    58. Reece JC, Martyushev A, Petravic J, Grimm A, Gooneratne S, Amaresena T, De Rose R, Loh L, Davenport MP, Kent SJ. Measuring turnover of SIV DNA in resting CD4+ T cells using pyrosequencing: implications for the timing of HIV eradication therapies. PLoS One. 2014; 9(4):e93330. PMID: 24710023.
      View in: PubMed
    59. Qui?ones-Parra S, Grant E, Loh L, Nguyen TH, Campbell KA, Tong SY, Miller A, Doherty PC, Vijaykrishna D, Rossjohn J, Gras S, Kedzierska K. Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1049-54. PMID: 24395804.
      View in: PubMed
    60. Leeansyah E, Loh L, Nixon DF, Sandberg JK. Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development. Nat Commun. 2014; 5:3143. PMID: 24452018.
      View in: PubMed
    61. Reece J, Petravic J, Balamurali M, Loh L, Gooneratne S, De Rose R, Kent SJ, Davenport MP. An "escape clock" for estimating the turnover of SIV DNA in resting CD4? T cells. PLoS Pathog. 2012; 8(4):e1002615. PMID: 22496643.
      View in: PubMed
    62. Reece JC, Loh L, Alcantara S, Fernandez CS, Stambas J, Sexton A, De Rose R, Petravic J, Davenport MP, Kent SJ. Timing of immune escape linked to success or failure of vaccination. PLoS One. 2010 Sep 16; 5(9). PMID: 20862289.
      View in: PubMed
    63. Sexton A, De Rose R, Reece JC, Alcantara S, Loh L, Moffat JM, Laurie K, Hurt A, Doherty PC, Turner SJ, Kent SJ, Stambas J. Evaluation of recombinant influenza virus-simian immunodeficiency virus vaccines in macaques. J Virol. 2009 Aug; 83(15):7619-28. PMID: 19439474.
      View in: PubMed
    64. Loh L, Reece JC, Fernandez CS, Alcantara S, Center R, Howard J, Purcell DF, Balamurali M, Petravic J, Davenport MP, Kent SJ. Complexity of the inoculum determines the rate of reversion of SIV Gag CD8 T cell mutant virus and outcome of infection. PLoS Pathog. 2009 Apr; 5(4):e1000378. PMID: 19360124.
      View in: PubMed
    65. De Rose R, Mason RD, Loh L, Peut V, Smith MZ, Fernandez CS, Alcantara S, Amarasena T, Reece J, Seddiki N, Kelleher AD, Zaunders J, Kent SJ. Safety, immunogenicity and efficacy of peptide-pulsed cellular immunotherapy in macaques. J Med Primatol. 2008 Dec; 37 Suppl 2:69-78. PMID: 19187433.
      View in: PubMed
    66. Mason RD, Alcantara S, Peut V, Loh L, Lifson JD, De Rose R, Kent SJ. Inactivated simian immunodeficiency virus-pulsed autologous fresh blood cells as an immunotherapy strategy. J Virol. 2009 Feb; 83(3):1501-10. PMID: 19019966.
      View in: PubMed
    67. Loh L, Kent SJ. Quantification of simian immunodeficiency virus cytotoxic T lymphocyte escape mutant viruses. AIDS Res Hum Retroviruses. 2008 Aug; 24(8):1067-72. PMID: 18620496.
      View in: PubMed
    68. De Rose R, Fernandez CS, Loh L, Peut V, Mason RD, Alcantara S, Reece J, Kent SJ. Delivery of immunotherapy with peptide-pulsed blood in macaques. Virology. 2008 Sep 01; 378(2):201-4. PMID: 18620724.
      View in: PubMed
    69. De Rose R, Fernandez CS, Smith MZ, Batten CJ, Alc?ntara S, Peut V, Rollman E, Loh L, Mason RD, Wilson K, Law MG, Handley AJ, Kent SJ. Control of viremia and prevention of AIDS following immunotherapy of SIV-infected macaques with peptide-pulsed blood. PLoS Pathog. 2008 May 02; 4(5):e1000055. PMID: 18451982.
      View in: PubMed
    70. Kent SJ, De Rose R, Mokhonov VV, Mokhonova EI, Fernandez CS, Alcantara S, Rollman E, Mason RD, Loh L, Peut V, Reece JC, Wang XJ, Wilson KM, Suhrbier A, Khromykh A. Evaluation of recombinant Kunjin replicon SIV vaccines for protective efficacy in macaques. Virology. 2008 May 10; 374(2):528-34. PMID: 18272194.
      View in: PubMed
    71. Loh L, Petravic J, Batten CJ, Davenport MP, Kent SJ. Vaccination and timing influence SIV immune escape viral dynamics in vivo. PLoS Pathog. 2008 Jan; 4(1):e12. PMID: 18225952.
      View in: PubMed
    72. Loh L, Batten CJ, Petravic J, Davenport MP, Kent SJ. In vivo fitness costs of different Gag CD8 T-cell escape mutant simian-human immunodeficiency viruses for macaques. J Virol. 2007 May; 81(10):5418-22. PMID: 17344299.
      View in: PubMed
    Loh's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description

    Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)